CANCER RESEARCH CAREER ENHANCEMENT AND RELATED ACTIVITIES PROJECT SUMMARY The Mayo Clinic Cancer Center (MCCC) embraces career enhancement and education as one of its core missions. NIH-funded training mechanisms and Mayo Clinic philanthropy support cancer researchers at all career levels. Faculty and trainees benefit from MCCC seminars and conferences that provide ongoing state-of-the-art education updates.
The specific aims of the MCCC Career Enhancement and Related Activities are as follows: 1) to mentor and develop the next generation of high-achieving cancer researchers, and 2) to provide MCCC trainees and faculty with continuing research and medical education to further their career development and to support the MCCC mission of improving cancer prevention, detection, diagnosis, and therapy. The MCCC is well-positioned to accomplish these aims, as demonstrated by its 1) 12 NIH-funded training programs whose trainees have amassed 600+ cancer-focused publications this past grant cycle; 2) 13 competitive, philanthropically- funded, MCCC grant mechanisms that award $50,000 to $100,000 of annual support to each junior investigator 3) the competitive, philanthropically-funded Eagles mechanism that annually awards over $500,000 in direct research funding, primarily to junior cancer investigators; 4) career development opportunities within the MCCC's SPORE's, which forge strong alignment between MCCC research priorities and the interests of junior investigators; 5) institutional salary subsidization of trainees on K awards ($20M allocated since 2012 to cancer researchers) and financial incentives for junior MCCC trainees to apply for NIH funding, both of which are intended to retain junior cancer investigators within academic medicine; and 6) a commitment to diversity that permeates the MCCC's career enhancement and educational efforts and that allows the MCCC to train, to recruit, and to promote high-achieving cancer researchers. In view of its commitment to career enhancement and education, the MCCC is poised to accomplish its specific aims and to train the next generation of cancer researchers who will conduct ground-breaking research that will improve the lives of cancer patients.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA015083-47
Application #
10113575
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
1997-04-25
Project End
2024-02-29
Budget Start
2021-03-01
Budget End
2022-02-28
Support Year
47
Fiscal Year
2021
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
006471700
City
Rochester
State
MN
Country
United States
Zip Code
55905
Wu, Dongyan; Yang, Haitao; Winham, Stacey J et al. (2018) Mediation analysis of alcohol consumption, DNA methylation, and epithelial ovarian cancer. J Hum Genet 63:339-348
Leon-Ferre, Roberto A; Polley, Mei-Yin; Liu, Heshan et al. (2018) Impact of histopathology, tumor-infiltrating lymphocytes, and adjuvant chemotherapy on prognosis of triple-negative breast cancer. Breast Cancer Res Treat 167:89-99
Jahanseir, Khadijeh; Xing, Deyin; Greipp, Patricia T et al. (2018) PDGFB Rearrangements in Dermatofibrosarcoma Protuberans of the Vulva: A Study of 11 Cases Including Myxoid and Fibrosarcomatous Variants. Int J Gynecol Pathol 37:537-546
Painter, Jodie N; O'Mara, Tracy A; Morris, Andrew P et al. (2018) Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses. Cancer Med 7:1978-1987
Yu, Jia; Qin, Bo; Moyer, Ann M et al. (2018) DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine. J Clin Invest 128:2376-2388
Sugihara, Takaaki; Werneburg, Nathan W; Hernandez, Matthew C et al. (2018) YAP Tyrosine Phosphorylation and Nuclear Localization in Cholangiocarcinoma Cells Are Regulated by LCK and Independent of LATS Activity. Mol Cancer Res 16:1556-1567
Natanzon, Yanina; Goode, Ellen L; Cunningham, Julie M (2018) Epigenetics in ovarian cancer. Semin Cancer Biol 51:160-169
Kleinstern, Geffen; Camp, Nicola J; Goldin, Lynn R et al. (2018) Association of polygenic risk score with the risk of chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis. Blood 131:2541-2551
Liu, Gang; Mukherjee, Bhramar; Lee, Seunggeun et al. (2018) Robust Tests for Additive Gene-Environment Interaction in Case-Control Studies Using Gene-Environment Independence. Am J Epidemiol 187:366-377
Ong, Jue-Sheng; Hwang, Liang-Dar; Cuellar-Partida, Gabriel et al. (2018) Assessment of moderate coffee consumption and risk of epithelial ovarian cancer: a Mendelian randomization study. Int J Epidemiol 47:450-459

Showing the most recent 10 out of 1129 publications