Abstract

The Fred Hutchinson Cancer Research Center is an independent, non-profit research center, incorporated in 1971 and established exclusively for cancer research. The Center is organized into five divisions: the three scientific Divisions of Basic Sciences, Clinical Research and Public Health Sciences, and the Administration and Development divisions. Scientific programs include: Basic Sciences - Biochemical Oncology, Cell Biology, Developmental Biologiy, Genetics, Molecular Biology and Immunology, Molecular Medicine (interdisciplinary), Tumor Biology and Viral Oncology. Clinical Research - Allogeneic Marrow Transplant for Malignant Disease, Autologous Marrow Transplantation, Biological Response Modifiers, Chemoimmunotherapy and Syngenic Marrow Transplantation, Experimental Pathology (interdisciplinary), Human Immunogenetics, Infectious Diseases, Pain & Toxicity Research, Pediatric Oncology, Clinical Pathology, Supportive Care and Transplantation Biology. Public Health Sciences - Biostatistics, Epidemiology and Cancer Prevention. Newly developing programs included in this proposal are Gastroenterology and Nutrition Research. This application requests renewal of the Center's existing Caner Center Support Grant (Comprehensive). Support requested will continue the development and maintenance of support for professional personnel (Senior Leadership, Major Program Heads, and Staff Investigators), division administration and planning, shared resources and development of the new programs mentioned above.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA015704-18
Application #
3101484
Study Section
Cancer Center Support Review Committee (CCS)
Project Start
1977-01-01
Project End
1992-12-31
Budget Start
1991-01-01
Budget End
1991-12-31
Support Year
18
Fiscal Year
1991
Total Cost
Indirect Cost

  Institution

Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
075524595
City
Seattle
State
WA
Country
United States
Zip Code
98109

  Publications

Jeong, Kyoung Sook; Zhou, Jin; Griffin, Stephanie C et al. (2018) MicroRNA Changes in Firefighters. J Occup Environ Med 60:469-474
Appelbaum, Jacob; Wells, David; Hiatt, Joseph B et al. (2018) Fatal enteric plexus neuropathy after one dose of ipilimumab plus nivolumab: a case report. J Immunother Cancer 6:82
Blair, Kris M; Mears, Kevin S; Taylor, Jennifer A et al. (2018) The Helicobacter pylori cell shape promoting protein Csd5 interacts with the cell wall, MurF, and the bacterial cytoskeleton. Mol Microbiol 110:114-127
Talarico, Sarah; Korson, Andrew S; Leverich, Christina K et al. (2018) High prevalence of Helicobacter pylori clarithromycin resistance mutations among Seattle patients measured by droplet digital PCR. Helicobacter 23:e12472
Bhatia, Shailender; Miller, Natalie J; Lu, Hailing et al. (2018) Intratumoral G100, a TLR4 Agonist, Induces Antitumor Immune Responses and Tumor Regression in Patients with Merkel Cell Carcinoma. Clin Cancer Res :
Chozinski, Tyler J; Mao, Chenyi; Halpern, Aaron R et al. (2018) Volumetric, Nanoscale Optical Imaging of Mouse and Human Kidney via Expansion Microscopy. Sci Rep 8:10396
Holly, Mayumi K; Smith, Jason G (2018) Adenovirus infection of human enteroids reveals interferon sensitivity and preferential infection of goblet cells. J Virol :
Cheng, Heather H (2018) The resounding effect of DNA repair deficiency in prostate cancer. Urol Oncol 36:385-388
Poudel, Kumud R; Roh-Johnson, Minna; Su, Allen et al. (2018) Competition between TIAM1 and Membranes Balances Endophilin A3 Activity in Cancer Metastasis. Dev Cell 45:738-752.e6
Eaton, Keith D; Romine, Perrin E; Goodman, Gary E et al. (2018) Inflammatory Gene Polymorphisms in Lung Cancer Susceptibility. J Thorac Oncol 13:649-659

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