Abstract

The Fred Hutchinson Cancer Research Center is an independent, non-profit research center, incorporated in 1971 and established exclusively for cancer research. The Center is organized into five divisions: the three scientific Divisions of Basic Sciences, Clinical Research and Public Health Sciences, and the Administration and Development divisions. Scientific programs include: Basic Sciences - Biochemical Oncology, Cell Biology, Developmental Biologiy, Genetics, Molecular Biology and Immunology, Molecular Medicine (interdisciplinary), Tumor Biology and Viral Oncology. Clinical Research - Allogeneic Marrow Transplant for Malignant Disease, Autologous Marrow Transplantation, Biological Response Modifiers, Chemoimmunotherapy and Syngenic Marrow Transplantation, Experimental Pathology (interdisciplinary), Human Immunogenetics, Infectious Diseases, Pain & Toxicity Research, Pediatric Oncology, Clinical Pathology, Supportive Care and Transplantation Biology. Public Health Sciences - Biostatistics, Epidemiology and Cancer Prevention. Newly developing programs included in this proposal are Gastroenterology and Nutrition Research. This application requests renewal of the Center's existing Caner Center Support Grant (Comprehensive). Support requested will continue the development and maintenance of support for professional personnel (Senior Leadership, Major Program Heads, and Staff Investigators), division administration and planning, shared resources and development of the new programs mentioned above.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA015704-19
Application #
3101485
Study Section
Cancer Center Support Review Committee (CCS)
Project Start
1977-01-01
Project End
1992-12-31
Budget Start
1992-02-28
Budget End
1992-12-31
Support Year
19
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
075524595
City
Seattle
State
WA
Country
United States
Zip Code
98109

  Publications

Briant, Katherine J; Sanchez, Janeth I; Ibarra, Genoveva et al. (2018) Using a Culturally Tailored Intervention to Increase Colorectal Cancer Knowledge and Screening among Hispanics in a Rural Community. Cancer Epidemiol Biomarkers Prev 27:1283-1288
Xu, Chang; Nikolova, Olga; Basom, Ryan S et al. (2018) Functional Precision Medicine Identifies Novel Druggable Targets and Therapeutic Options in Head and Neck Cancer. Clin Cancer Res 24:2828-2843
Miller, Chris P; Tsuchida, Connor; Zheng, Ying et al. (2018) A 3D Human Renal Cell Carcinoma-on-a-Chip for the Study of Tumor Angiogenesis. Neoplasia 20:610-620
Baker, K Scott; Syrjala, Karen L (2018) Long-term complications in adolescent and young adult leukemia survivors. Hematology Am Soc Hematol Educ Program 2018:146-153
Gavvovidis, Ioannis; Leisegang, Matthias; Willimsky, Gerald et al. (2018) Targeting Merkel Cell Carcinoma by Engineered T Cells Specific to T-Antigens of Merkel Cell Polyomavirus. Clin Cancer Res 24:3644-3655
Paulson, K G; Voillet, V; McAfee, M S et al. (2018) Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLA. Nat Commun 9:3868
Puronen, Camille E; Cassaday, Ryan D; Stevenson, Philip A et al. (2018) Long-Term Follow-Up of 90Y-Ibritumomab Tiuxetan, Fludarabine, and Total Body Irradiation-Based Nonmyeloablative Allogeneic Transplant Conditioning for Persistent High-Risk B Cell Lymphoma. Biol Blood Marrow Transplant 24:2211-2215
Witzky, Anne; Hummels, Katherine R; Tollerson 2nd, Rodney et al. (2018) EF-P Posttranslational Modification Has Variable Impact on Polyproline Translation in Bacillus subtilis. MBio 9:
Rosenthal, Elisabeth A; Shirts, Brian H; Amendola, Laura M et al. (2018) Rare loss of function variants in candidate genes and risk of colorectal cancer. Hum Genet 137:795-806
Verboon, Jeffrey M; Decker, Jacob R; Nakamura, Mitsutoshi et al. (2018) Correction: Wash exhibits context-dependent phenotypes and, along with the WASH regulatory complex, regulates Drosophila oogenesis (doi:10.1242/211573). J Cell Sci 131:

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