The Biotechnology Shared Resource (previously the Microchemistry Shared Resource) was established in 1987 to provide researchers with access to the automated chemistries of biopolymer synthesis and sequencing. Its continued growth and use clearly demonstrate the need for this laboratory. The mission of the resource is to provide researcher an on-site, cost efficient resource for custom DNA and Peptide synthesis, automated (fluorescent) DNA sequencing and protein sequencing. Mass spectrometry services will be introduced in the fall of 1997. A high efficiency genotyping and sequencing satellite operation will be established in spring of 1998 which will provide support for peer reviewed research in several areas, including the role of gene/environment interaction in cancer, mapping and cloning novel cancer genes, overcoming HLA mismatch in organ transplantation and understanding the significance of cancer predisposing genes in the general population. The resource has had significant experience and demonstrated success in addressing the needs of large volume users. This expertise, coupled with an established administrative structure will ensure appropriate coordination and support of this satellite operation. The staff of the resource works in partnership with researchers from all divisions at the FHCRC to provide technological expertise and support for peer-reviewed research.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA015704-29S1
Application #
6576528
Study Section
Project Start
2002-03-21
Project End
2002-12-31
Budget Start
Budget End
Support Year
29
Fiscal Year
2002
Total Cost
Indirect Cost
Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
075524595
City
Seattle
State
WA
Country
United States
Zip Code
98109
Herman, Daniel S; Smith, Christina; Liu, Chang et al. (2018) Efficient Detection of Copy Number Mutations in PMS2 Exons with a Close Homolog. J Mol Diagn 20:512-521
Birnbaum, Jeanette K; Duggan, Catherine; Anderson, Benjamin O et al. (2018) Early detection and treatment strategies for breast cancer in low-income and upper middle-income countries: a modelling study. Lancet Glob Health 6:e885-e893
Partridge, Emma K; Neuhouser, Marian L; Breymeyer, Kara et al. (2018) Comparison of Nutrient Estimates Based on Food Volume versus Weight: Implications for Dietary Assessment Methods. Nutrients 10:
Jia, Deshui; Augert, Arnaud; Kim, Dong-Wook et al. (2018) Crebbp Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition. Cancer Discov 8:1422-1437
Kuzma, Jessica N; Cromer, Gail; Hagman, Derek K et al. (2018) Consuming glucose-sweetened, not fructose-sweetened, beverages increases fasting insulin in healthy humans. Eur J Clin Nutr :
Neumeyer, Sonja; Banbury, Barbara L; Arndt, Volker et al. (2018) Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer. Br J Cancer 118:1639-1647
Puré, Ellen; Hingorani, Sunil R (2018) Mesenchymal Cell Plasticity and Perfidy in Epithelial Malignancy. Trends Cancer 4:273-277
Yu, Hsiang; Cheng, Yu-Jen; Wang, Ching-Yun (2018) Methods for multivariate recurrent event data with measurement error and informative censoring. Biometrics 74:966-976
Linden, Hannah M; Peterson, Lanell M; Fowler, Amy M (2018) Clinical Potential of Estrogen and Progesterone Receptor Imaging. PET Clin 13:415-422
Barault, Ludovic; Amatu, Alessio; Siravegna, Giulia et al. (2018) Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer. Gut 67:1995-2005

Showing the most recent 10 out of 1267 publications