DEVELOPMENTAL FUNDS Developmental funds were used in the last cycle for recruiting new investigators, supporting developmental projects, creating new shared resources, and helping fund several key staff investigators. Several outstanding investigators who received recruitment funds during the project period would not have come to Seattle without the extra support that was offered through the availability of CCSG New Investigator Awards, distributed to faculty from Fred Hutch (FH), University of Washington (UW), and Seattle Children?s (SC). The availability of CCSG Pilot Award funding provides investigators a very tangible benefit of Cancer Consortium membership and has stimulated new initiatives and collaborations that would otherwise not have occurred, particularly in transdisciplinary science, cancer health disparities, and catchment area health. Funds to catalyze new Shared Resource development have afforded Consortium members access to technologies and expertise that would otherwise not be sustainable in an individual laboratory or even on an institutional basis. Finally, developmental funds help support staff investigators focused on enhancing our community outreach and engagement efforts. During the last grant period, Developmental Funds supported the recruitment of 33 productive Consortium faculty members in areas of strategic growth and funded 45 Pilot Award projects. Together, these faculty members and pilot projects gave rise to a total of 439 publications and over $28M in new follow-on funding. In the last cycle, Developmental Funds were instrumental in the formation of the Hutch Data Commonwealth and supported two Special Populations Staff Investigators, both of whom continue to lead efforts to reduce disparities in underserved populations and one of whom has become the new Director of our Office of Community Outreach & Engagement. In this application, we are requesting funds to support future Pilot and New Investigator Awards, two new Special Populations Staff Investigators, and a Preclinical Models Shared Resource.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA015704-45
Application #
9853668
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2020-01-01
Budget End
2020-12-31
Support Year
45
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
078200995
City
Seattle
State
WA
Country
United States
Zip Code
98109
Blair, Kris M; Mears, Kevin S; Taylor, Jennifer A et al. (2018) The Helicobacter pylori cell shape promoting protein Csd5 interacts with the cell wall, MurF, and the bacterial cytoskeleton. Mol Microbiol 110:114-127
Jeong, Kyoung Sook; Zhou, Jin; Griffin, Stephanie C et al. (2018) MicroRNA Changes in Firefighters. J Occup Environ Med 60:469-474
Appelbaum, Jacob; Wells, David; Hiatt, Joseph B et al. (2018) Fatal enteric plexus neuropathy after one dose of ipilimumab plus nivolumab: a case report. J Immunother Cancer 6:82
Chozinski, Tyler J; Mao, Chenyi; Halpern, Aaron R et al. (2018) Volumetric, Nanoscale Optical Imaging of Mouse and Human Kidney via Expansion Microscopy. Sci Rep 8:10396
Talarico, Sarah; Korson, Andrew S; Leverich, Christina K et al. (2018) High prevalence of Helicobacter pylori clarithromycin resistance mutations among Seattle patients measured by droplet digital PCR. Helicobacter 23:e12472
Bhatia, Shailender; Miller, Natalie J; Lu, Hailing et al. (2018) Intratumoral G100, a TLR4 Agonist, Induces Antitumor Immune Responses and Tumor Regression in Patients with Merkel Cell Carcinoma. Clin Cancer Res :
Poudel, Kumud R; Roh-Johnson, Minna; Su, Allen et al. (2018) Competition between TIAM1 and Membranes Balances Endophilin A3 Activity in Cancer Metastasis. Dev Cell 45:738-752.e6
Holly, Mayumi K; Smith, Jason G (2018) Adenovirus infection of human enteroids reveals interferon sensitivity and preferential infection of goblet cells. J Virol :
Cheng, Heather H (2018) The resounding effect of DNA repair deficiency in prostate cancer. Urol Oncol 36:385-388
Bar, Merav; Flowers, Mary E D; Storer, Barry E et al. (2018) Reversal of Low Donor Chimerism after Hematopoietic Cell Transplantation Using Pentostatin and Donor Lymphocyte Infusion: A Prospective Phase II Multicenter Trial. Biol Blood Marrow Transplant 24:308-313

Showing the most recent 10 out of 1267 publications