Abstract

The Peptide and Protein Engineering Laboratory (PPEL) provides synthetic peptides, capillary electrophoresis, solid phase sequencing, covalent protein sequencing, amino acid analysis and synthesis of overlapping peptides. It is equipped with a Biosearch/Milligen peptide synthesizer (model 9600), Milligen protein sequencer (model 6600), Advanced Chem Tech multiple peptide synthesizer (model 450), Beckman capillary electrophoresis unit, Waters HPLC workstation (model 820), Beckman HPLCs, lyophilizers, a computer for protein modeling, as well as other requisite support devices.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA016058-24S2
Application #
6218791
Study Section
Project Start
1998-07-01
Project End
1999-11-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
24
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
Ohio State University
Department
Type
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210

  Publications

Brasky, Theodore M; Hinton, Alice; Doogan, Nathan J et al. (2018) Characteristics of the Tobacco User Adult Cohort in Urban and Rural Ohio. Tob Regul Sci 4:614-630
Saini, Uksha; Suarez, Adrian A; Naidu, Shan et al. (2018) STAT3/PIAS3 Levels Serve as ""Early Signature"" Genes in the Development of High-Grade Serous Carcinoma from the Fallopian Tube. Cancer Res 78:1739-1750
Olaverria Salavaggione, Gonzalo N; Duggan, Megan C; Carson, William E (2018) Analysis of MLN4924 (pevonedistat) as a potential therapeutic agent in malignant melanoma. Melanoma Res 28:390-397
Jones, Caitlin E; Hammer, Anisha M; Cho, YouJin et al. (2018) Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland. Neoplasia 21:132-145
Fenn, J Daniel; Monsma, Paula C; Brown, Anthony (2018) Axonal neurofilaments exhibit frequent and complex folding behaviors. Cytoskeleton (Hoboken) 75:258-280
Zhang, Lingling; Yu, Jianhua; Wei, Wei (2018) Advance in Targeted Immunotherapy for Graft-Versus-Host Disease. Front Immunol 9:1087
Jasinski, Daniel L; Li, Hui; Guo, Peixuan (2018) The Effect of Size and Shape of RNA Nanoparticles on Biodistribution. Mol Ther 26:784-792
Gordillo, Gayle M (2018) Reply: Urinary Excretion of MicroRNA-126 Is a Biomarker for Hemangioma Proliferation. Plast Reconstr Surg 141:320e
Ott, Christopher J; Federation, Alexander J; Schwartz, Logan S et al. (2018) Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia. Cancer Cell 34:982-995.e7
Willis, William L; Wang, Linan; Wada, Takuma Tsuzuki et al. (2018) The proinflammatory protein HMGB1 is a substrate of transglutaminase-2 and forms high-molecular weight complexes with autoantigens. J Biol Chem 293:8394-8409

Showing the most recent 10 out of 2602 publications