The Nucleic Acids Sequencing and Synthesis Resource (NASSR) was established in fall of 1986. Since January, 1992, this facility has been supported entirely by the CCSG, charge-back fees, and other cancer center resources. The facility now supports automated DNA Sequencing, DNA synthesis and purification, radioanalytic imaging, and instrumentation for PCR amplification. The Laboratory has continued to maintain a steady throughput of normal, modified, large scale and specialty oligonucleotide synthesis, and the fees continue to be very favorable for Massey Cancer Center users. However, the balance between DNA synthesis and sequence determination has clearly shifted towards sequencing during the past funding period. The Laboratory offers a variety of sequencing services, including plasmid, cosmid, BAC, and PCR fragment sequencing. A new PE/ABD 377 Prism DNA Sequencer is being acquired through the mechanism of an NIH Instrumentation award. This instrument will enhance the throughput of the Nucleic Acids Lab and to extend its capabilities to genetic analysis. This instrumentation will be installed in the of summer of 1998.
| Kazarian, Elizabeth; Son, HyunYoung; Sapao, Paulene et al. (2018) SPAG17 Is Required for Male Germ Cell Differentiation and Fertility. Int J Mol Sci 19: |
| Farrell, Nicholas P; Gorle, Anil K; Peterson, Erica J et al. (2018) Metalloglycomics. Met Ions Life Sci 18: |
| Ordoñez, José A; Bandyopadhyay, Dipankar; Lachos, Victor H et al. (2018) Geostatistical estimation and prediction for censored responses. Spat Stat 23:109-123 |
| Abeyawardhane, Dinendra L; Fernández, Ricardo D; Murgas, Cody J et al. (2018) Iron Redox Chemistry Promotes Antiparallel Oligomerization of ?-Synuclein. J Am Chem Soc 140:5028-5032 |
| Zhang, Yong; Liu, Hong; Li, Wei et al. (2018) Intraflagellar transporter protein 140 (IFT140), a component of IFT-A complex, is essential for male fertility and spermiogenesis in mice. Cytoskeleton (Hoboken) 75:70-84 |
| Singh, Dhirendra P; Kaur, Gagandeep; Bagam, Prathyusha et al. (2018) Membrane microdomains regulate NLRP10- and NLRP12-dependent signalling in A549 cells challenged with cigarette smoke extract. Arch Toxicol 92:1767-1783 |
| Lochmann, Timothy L; Floros, Konstantinos V; Naseri, Mitra et al. (2018) Venetoclax Is Effective in Small-Cell Lung Cancers with High BCL-2 Expression. Clin Cancer Res 24:360-369 |
| Zhou, Liang; Zhang, Yu; Sampath, Deepak et al. (2018) Flavopiridol enhances ABT-199 sensitivity in unfavourable-risk multiple myeloma cells in vitro and in vivo. Br J Cancer 118:388-397 |
| Huang, Dian; Leslie, Kevin A; Guest, Daniel et al. (2018) High-Speed Live-Cell Interferometry: A New Method for Quantifying Tumor Drug Resistance and Heterogeneity. Anal Chem 90:3299-3306 |
| Salman, Ali; Koparde, Vishal; Hall, Charles E et al. (2018) Determining the Quantitative Principles of T Cell Response to Antigenic Disparity in Stem Cell Transplantation. Front Immunol 9:2284 |
Showing the most recent 10 out of 586 publications
