Abstract

Developmental funds have played a key role in facilitating scientific growth and increased interdisciplinarycollaboration at Massey Cancer Center during the current funding period. As the Center will remain on asteep growth curve during the next 5 years, the specific goals to be pursued using developmental funds willbe the following. Facilitation of strategic expansion of scientific programs through new faculty recruitment, Fostering new intra-programmatic and inter-programmatic scientific collaborations and pursuit ofnovel hypotheses by bringing together investigators to collaborate on innovative pilot projects, and Development of new shared resources to promote and expand high priority scientific activities of theCancer Center.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA016059-28
Application #
7698805
Study Section
Subcommittee G - Education (NCI)
Project Start
2008-09-03
Project End
2011-04-30
Budget Start
2008-09-03
Budget End
2009-04-30
Support Year
28
Fiscal Year
2008
Total Cost
$86,462
Indirect Cost

  Institution

Name
Virginia Commonwealth University
Department
Type
DUNS #
105300446
City
Richmond
State
VA
Country
United States
Zip Code
23298

  Publications

Booth, Laurence; Roberts, Jane L; Rais, Rumeesa et al. (2018) [Neratinib + Valproate] exposure permanently reduces ERBB1 and RAS expression in 4T1 mammary tumors and enhances M1 macrophage infiltration. Oncotarget 9:6062-6074
Floros, Konstantinos V; Lochmann, Timothy L; Hu, Bin et al. (2018) Coamplification of miR-4728 protects HER2-amplified breast cancers from targeted therapy. Proc Natl Acad Sci U S A 115:E2594-E2603
Warthan, Michelle D; Washington, Sonya L; Franzese, Samone E et al. (2018) The role of endoplasmic reticulum aminopeptidase 2 in modulating immune detection of choriocarcinoma. Biol Reprod 98:309-322
Lv, Dong-Wen; Zhang, Kun; Li, Renfeng (2018) Interferon regulatory factor 8 regulates caspase-1 expression to facilitate Epstein-Barr virus reactivation in response to B cell receptor stimulation and chemical induction. PLoS Pathog 14:e1006868
Rizzo, Juliana; Colombo, Ana C; Zamith-Miranda, Daniel et al. (2018) The putative flippase Apt1 is required for intracellular membrane architecture and biosynthesis of polysaccharide and lipids in Cryptococcus neoformans. Biochim Biophys Acta Mol Cell Res 1865:532-541
Brabec, Viktor; Kasparkova, Jana; Menon, Vijay et al. (2018) Polynuclear Platinum Complexes. Structural Diversity and DNA Binding. Met Ions Life Sci 18:
Liu, Runping; Li, Xiaojiaoyang; Huang, Zhiming et al. (2018) C/EBP homologous protein-induced loss of intestinal epithelial stemness contributes to bile duct ligation-induced cholestatic liver injury in mice. Hepatology 67:1441-1457
Moro, Kazuki; Kawaguchi, Tsutomu; Tsuchida, Junko et al. (2018) Ceramide species are elevated in human breast cancer and are associated with less aggressiveness. Oncotarget 9:19874-19890
Talukdar, Sarmistha; Pradhan, Anjan K; Bhoopathi, Praveen et al. (2018) MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells. Proc Natl Acad Sci U S A 115:5768-5773
Luzi, Nicole M; Lyons, Charles E; Peterson, Darrell L et al. (2018) Kinetics and inhibition studies of the L205R mutant of cAMP-dependent protein kinase involved in Cushing's syndrome. FEBS Open Bio 8:606-613

Showing the most recent 10 out of 586 publications