The CRIS Shared Resource serves as both a medical informatics and as a.service core. It consists of fourmain components: the Massey Cancer Center Information System (MCCIS), the Automated CancerExtraction (ACE) Application, the Clinical Trials Eligibility Database (CTED), and the clinical researchdatabase system (Oncore ). With the exception of Oncore , each component has been developed at VCUand is linked both technologically in terms of interrelated data sources and software as well as functionally interms of personnel and services provided. The system design is based on inter-operability and communitystandards, with potential extensibility a strong development consideration. The core data come from linkageof multiple electronic sources across the VCU health care system including: inpatient and outpatient facilities,and the MCC In addition, primary data entered by research staff are a component of the CTED andOncore . The data from the core are available and downloadable both as source documents (such asoriginal surgical pathology reports) and as analyzable datasets developed by core personnel to answerspecific research questions. In addition to the data, consultative and analytic services are provided throughthis Shared Resource. These services range from providing population numbers for grant preparation tolinkage and analysis of complex data sets developed in response to investigator requests. The MCCIS is theoldest component of the core, originally developed in 1998, with the linkage of VCU claims data for inpatientand outpatient services. The MCCIS serves as the primary component providing analysis services, linkingand utilizing data from the MCCIS and the other three core components for these analyses. The ACEapplication is the newest component and was implemented in December of 2006. ACE serves as the initialprocessing system for screening messages for cancer relevance and for storage of all electronic sourcesfrom the VCUHS and linking the data to CTED and the hospital cancer registry. The most recent SQL Serverversion of CTED was implemented in April of 2007. The commercial application used for administrative andclinical research in tracking of oversight and clinical trials activity was implemented in 2005. Currently,integration and equivalency of Oncore with the other three components is being developed to provide autouploadingof key information such as demographics, as well as direct access to source documentation fromthe other three components of CRIS for research staff while in the Oncore environment.
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