Abstract

The Virus Vector Shared Resource (WSR) provides technical and consulting services for investigators who need virus vectors for basic laboratory and animal studies. Virus vectors for expressing proteins ectopically and knocking down gene expression are offered to Cancer Center members and VCD investigators for costs well below commercial sources. Until recently, the predominant service and needs of investigators have been to produce adenovirus;however, during the past year, the requests for lentivirus have increased significantly, a trend we expect to continue in the future. The added-value of the WSR for Massey Cancer Center members, in particular junior faculty, is critical and cannot be overstated.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016059-29
Application #
7826932
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2009-05-01
Budget End
2010-04-30
Support Year
29
Fiscal Year
2009
Total Cost
$39,525
Indirect Cost

  Institution

Name
Virginia Commonwealth University
Department
Type
DUNS #
105300446
City
Richmond
State
VA
Country
United States
Zip Code
23298

  Publications

Sharma, Kanika; Vu, Thien-Trang; Cook, Wade et al. (2018) p53-independent Noxa induction by cisplatin is regulated by ATF3/ATF4 in head and neck squamous cell carcinoma cells. Mol Oncol 12:788-798
Rahmani, Mohamed; Nkwocha, Jewel; Hawkins, Elisa et al. (2018) Cotargeting BCL-2 and PI3K Induces BAX-Dependent Mitochondrial Apoptosis in AML Cells. Cancer Res 78:3075-3086
Martin, Rebecca K; Damle, Sheela R; Valentine, Yolander A et al. (2018) B1 Cell IgE Impedes Mast Cell-Mediated Enhancement of Parasite Expulsion through B2 IgE Blockade. Cell Rep 22:1824-1834
Powell, Melissa A; Black, Raiford T; Smith, Terry L et al. (2018) Mild Fluid Percussion Injury Induces Diffuse Axonal Damage and Reactive Synaptic Plasticity in the Mouse Olfactory Bulb. Neuroscience 371:106-118
Vrzalikova, K; Ibrahim, M; Vockerodt, M et al. (2018) S1PR1 drives a feedforward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells. Leukemia 32:214-223
Stockstill, Katherine; Doyle, Timothy M; Yan, Xisheng et al. (2018) Dysregulation of sphingolipid metabolism contributes to bortezomib-induced neuropathic pain. J Exp Med 215:1301-1313
Mitrano, Darlene A; Jackson, Kelsey; Finley, Samantha et al. (2018) ?1b-Adrenergic Receptor Localization and Relationship to the D1-Dopamine Receptor in the Rat Nucleus Accumbens. Neuroscience 371:126-137
Ma, Yibao; Temkin, Sarah M; Hawkridge, Adam M et al. (2018) Fatty acid oxidation: An emerging facet of metabolic transformation in cancer. Cancer Lett 435:92-100
Anscher, Mitchell S; Chang, Michael G; Moghanaki, Drew et al. (2018) A Phase II Study to Prevent Radiation-induced Rectal Injury With Lovastatin. Am J Clin Oncol 41:544-548
Menezes, Mitchell E; Bhoopathi, Praveen; Pradhan, Anjan K et al. (2018) Role of MDA-7/IL-24 a Multifunction Protein in Human Diseases. Adv Cancer Res 138:143-182

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