Abstract

As a Research Staff Investigator, Dr Steven Grossman will bridge the Cancer Molecular Genetics (CMG) and Developmental Therapeutics (DT) programs together, through his preclinical and research interests and his membership in both programs. His laboratory research in p53 biology, and clinical and translational research in gastrointestinal cancer, will be focal points around which additional collaborative and translational research is expected to grow. Dr Grossman will play a special role in bringing together multiple basic scientists, prevention and control researchers, and translational-clinical investigators in gastrointestinal cancer at the Center to develop a highly interactive translation focus in that high priority area.

Public Health Relevance

In his position as a Research Staff Investigator. Dr Steven Grossman contribute to the public health by expanding the knowledge base of p53 biology and translating this information into clinical trials for the treatment of gastrointestinal cancer.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA016059-31
Application #
8299699
Study Section
Subcommittee G - Education (NCI)
Project Start
1978-12-01
Project End
2017-04-30
Budget Start
2012-08-30
Budget End
2013-04-30
Support Year
31
Fiscal Year
2012
Total Cost
$36,850
Indirect Cost
$12,606

  Institution

Name
Virginia Commonwealth University
Department
Type
DUNS #
105300446
City
Richmond
State
VA
Country
United States
Zip Code
23298

  Publications

Das, Swadesh K; Pradhan, Anjan K; Bhoopathi, Praveen et al. (2018) The MDA-9/Syntenin/IGF1R/STAT3 Axis Directs Prostate Cancer Invasion. Cancer Res 78:2852-2863
Lochmann, Timothy L; Powell, Krista M; Ham, Jungoh et al. (2018) Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma. Sci Transl Med 10:
Quinn, Bridget A; Deng, Xiaoyan; Colton, Adrianne et al. (2018) Increasing age predicts poor cervical cancer prognosis with subsequent effect on treatment and overall survival. Brachytherapy :
May, Peter; Garrido, Melissa M; Del Fabbro, Egidio et al. (2018) Does Modality Matter? Palliative Care Unit Associated With More Cost-Avoidance Than Consultations. J Pain Symptom Manage 55:766-774.e4
Mohan, Abhinav; Schlue, Kyle T; Kniffin, Alex F et al. (2018) Spatial Proliferation of Epithelial Cells Is Regulated by E-Cadherin Force. Biophys J 115:853-864
Farkas, Daniela; Thompson, A A Roger; Bhagwani, Aneel R et al. (2018) Toll-like Receptor 3 is a Therapeutic Target for Pulmonary Hypertension. Am J Respir Crit Care Med :
Booth, Laurence; Roberts, Jane L; Rais, Rumeesa et al. (2018) [Neratinib + Valproate] exposure permanently reduces ERBB1 and RAS expression in 4T1 mammary tumors and enhances M1 macrophage infiltration. Oncotarget 9:6062-6074
Floros, Konstantinos V; Lochmann, Timothy L; Hu, Bin et al. (2018) Coamplification of miR-4728 protects HER2-amplified breast cancers from targeted therapy. Proc Natl Acad Sci U S A 115:E2594-E2603
Warthan, Michelle D; Washington, Sonya L; Franzese, Samone E et al. (2018) The role of endoplasmic reticulum aminopeptidase 2 in modulating immune detection of choriocarcinoma. Biol Reprod 98:309-322
Lv, Dong-Wen; Zhang, Kun; Li, Renfeng (2018) Interferon regulatory factor 8 regulates caspase-1 expression to facilitate Epstein-Barr virus reactivation in response to B cell receptor stimulation and chemical induction. PLoS Pathog 14:e1006868

Showing the most recent 10 out of 586 publications