Abstract

As a Research Staff Investigator, Dr Steven Grossman will bridge the Cancer Molecular Genetics (CMG) and Developmental Therapeutics (DT) programs together, through his preclinical and research interests and his membership in both programs. His laboratory research in p53 biology, and clinical and translational research in gastrointestinal cancer, will be focal points around which additional collaborative and translational research is expected to grow. Dr Grossman will play a special role in bringing together multiple basic scientists, prevention and control researchers, and translational-clinical investigators in gastrointestinal cancer at the Center to develop a highly interactive translation focus in that high priority area.

Public Health Relevance

In his position as a Research Staff Investigator. Dr Steven Grossman contribute to the public health by expanding the knowledge base of p53 biology and translating this information into clinical trials for the treatment of gastrointestinal cancer.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA016059-31
Application #
8299699
Study Section
Subcommittee G - Education (NCI)
Project Start
1978-12-01
Project End
2017-04-30
Budget Start
2012-08-30
Budget End
2013-04-30
Support Year
31
Fiscal Year
2012
Total Cost
$36,850
Indirect Cost
$12,606

  Institution

Name
Virginia Commonwealth University
Department
Type
DUNS #
105300446
City
Richmond
State
VA
Country
United States
Zip Code
23298

  Publications

Radwa?ska, Malwina J; Jaskó?owski, Mateusz; Davydova, Elena et al. (2018) The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab. Acta Crystallogr D Struct Biol 74:681-689
Curry, Zachary A; Wilkerson, Jenny L; Bagdas, Deniz et al. (2018) Monoacylglycerol Lipase Inhibitors Reverse Paclitaxel-Induced Nociceptive Behavior and Proinflammatory Markers in a Mouse Model of Chemotherapy-Induced Neuropathy. J Pharmacol Exp Ther 366:169-183
Lancina 3rd, Michael G; Wang, Juan; Williamson, Geoffrey S et al. (2018) DenTimol as A Dendrimeric Timolol Analogue for Glaucoma Therapy: Synthesis and Preliminary Efficacy and Safety Assessment. Mol Pharm 15:2883-2889
Ginder, Gordon D; Williams Jr, David C (2018) Readers of DNA methylation, the MBD family as potential therapeutic targets. Pharmacol Ther 184:98-111
Karandashova, Sophia; Kummarapurugu, Apparao B; Zheng, Shuo et al. (2018) Neutrophil elastase increases airway ceramide levels via upregulation of serine palmitoyltransferase. Am J Physiol Lung Cell Mol Physiol 314:L206-L214
Vascak, Michal; Jin, Xiaotao; Jacobs, Kimberle M et al. (2018) Mild Traumatic Brain Injury Induces Structural and Functional Disconnection of Local Neocortical Inhibitory Networks via Parvalbumin Interneuron Diffuse Axonal Injury. Cereb Cortex 28:1625-1644
Chernoukhov, A; Hussein, A; Nkurunziza, S et al. (2018) Bayesian inference in time-varying additive hazards models with applications to disease mapping. Environmetrics 29:
Dai, Lu; Smith, Charles D; Foroozesh, Maryam et al. (2018) The sphingosine kinase 2 inhibitor ABC294640 displays anti-non-small cell lung cancer activities in vitro and in vivo. Int J Cancer 142:2153-2162
Iqbal, Emil S; Dods, Kara K; Hartman, Matthew C T (2018) Ribosomal incorporation of backbone modified amino acids via an editing-deficient aminoacyl-tRNA synthetase. Org Biomol Chem 16:1073-1078
Meader, Victoria Kathryn; John, Mallory G; Frias Batista, Laysa M et al. (2018) Radical Chemistry in a Femtosecond Laser Plasma: Photochemical Reduction of Ag? in Liquid Ammonia Solution. Molecules 23:

Showing the most recent 10 out of 586 publications