Biostatistics Core Facility (Michael J. Schell, Ph.D., Facility Director) The Biostatistics Core Facility provides statistical collaboration and support to cancer researchers at the UNC Lineberger Comprehensive Cancer Center. Center researchers' statistical needs encompass research/protocol design, technical support, and data analysis for clinical trials and for epidemiologic, cancer prevention and control, and basic science research. Technical support for the preparation and management of data for analysis is critical to the smooth functioning of this core. During the past year, the Biostatistics Core Facility has provided 4200 direct consultation hours plus 609 developmental hours to 42 Cancer Center members from eight programs, including 19 members of the Clinical Research Program. Of the consultation hours, 86% were to peer- reviewed members or for clinical protocol development; 98% were to members. Since the 1995 hiring of Dr. Schell as the full-time Facility Director, use has grown seven-fold and is continuing to increase. To meet this rising demand, in addition to Dr. Schell the Center has used institutional funds hired two masters-level biostatisticians. With continuing faculty expansion and the maturation of current and newly recruited clinical faculty, the Facility needs additional personnel. The Center and the Department of Biostatistics are currently searching for a second full-time, dedicated faculty statistician, and the Center is hiring a statistical programmer/analyst to provide needed statistical/technical support. The proposed CCSG budget totals of $270,828 will support 3.85 FTE of the total 6.80 FTE and 61% of the total budget of $440,777. The CCSG proposed budget represents a significant increase from the current budget of $77,993. The increase will provide needed support to help add two new positions (faculty statistician, statistical programmer/analyst) and to help support the three statistician positions added with institutional and grant funds since 1985. The CCSG contribution will increase from 32% to 61%. Institutional support, though proportionally lower (15% v. 32%), remains significant ($65,642).

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA016086-25
Application #
6398599
Study Section
Project Start
2000-05-01
Project End
2000-11-30
Budget Start
Budget End
Support Year
25
Fiscal Year
2000
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Hu, Peirong; Bi, Yanmin; Ma, Hong et al. (2018) Superior lentiviral vectors designed for BSL-0 environment abolish vector mobilization. Gene Ther 25:454-472
Townsley, Loni; Yannarell, Sarah M; Huynh, Tuanh Ngoc et al. (2018) Cyclic di-AMP Acts as an Extracellular Signal That Impacts Bacillus subtilis Biofilm Formation and Plant Attachment. MBio 9:
Schulfer, Anjelique F; Battaglia, Thomas; Alvarez, Yelina et al. (2018) Intergenerational transfer of antibiotic-perturbed microbiota enhances colitis in susceptible mice. Nat Microbiol 3:234-242
Hall, Marissa G; Mendel, Jennifer R; Noar, Seth M et al. (2018) Why smokers avoid cigarette pack risk messages: Two randomized clinical trials in the United States. Soc Sci Med 213:165-172
Cholon, Deborah M; Gentzsch, Martina (2018) Recent progress in translational cystic fibrosis research using precision medicine strategies. J Cyst Fibros 17:S52-S60
Tappata, Manaswita; Eluri, Swathi; Perjar, Irina et al. (2018) Association of mast cells with clinical, endoscopic, and histologic findings in adults with eosinophilic esophagitis. Allergy 73:2088-2092
Che, Tao; Majumdar, Susruta; Zaidi, Saheem A et al. (2018) Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor. Cell 172:55-67.e15
Cranston, Ross D; Cespedes, Michelle S; Paczuski, Pawel et al. (2018) High Baseline Anal Human Papillomavirus and Abnormal Anal Cytology in a Phase 3 Trial of the Quadrivalent Human Papillomavirus Vaccine in Human Immunodeficiency Virus-Infected Individuals Older Than 26 Years: ACTG 5298. Sex Transm Dis 45:266-271
DeBono, Nathan L; Robinson, Whitney R; Lund, Jennifer L et al. (2018) Race, Menopausal Hormone Therapy, and Invasive Breast Cancer in the Carolina Breast Cancer Study. J Womens Health (Larchmt) 27:377-386
Okolie, Onyinyechukwu; Irvin, David M; Bago, Juli R et al. (2018) Intra-cavity stem cell therapy inhibits tumor progression in a novel murine model of medulloblastoma surgical resection. PLoS One 13:e0198596

Showing the most recent 10 out of 1525 publications