PLANNING AND EVALUATION The LCCC internal and external advisory groups provided invaluable guidance in planning and evaluation of all the major initiatives and includes: ? The Senior Leadership Team, which is composed of the Director, Deputy Director and Associate Directors and meets weekly to evaluate progress in strategic LCCC initiatives. ? The Program Planning Committee, which meets monthly to evaluate progress of all important initiatives and includes institutional and Research Program Leaders, as well as the Senior Leadership Team. ? The Internal Advisory Board, comprised of institutional leaders including the Chancellor; Dean of the College of Arts and Sciences, Deans of the Schools of Medicine, Pharmacy, and Public Health and external advisors, and meets with the Director at least quarterly. ? The Scientific Advisory Board (SAB), which is comprised of expert external advisors, and which was expanded with the addition of two new members in 2018/19 to provide additional expertise in specific areas such as community outreach and engagement and clinical trials. There are now 14 members on the SAB with complementary expertise in basic, clinical, translational, and population sciences and administration. The SAB meets at least annually at the UNC LCCC. ? The Community Advisory Board (CAB), the 12 membered CAB meets quarterly with the Director and COE Leadership. The CAB is geographically, racially and ethnically representative of our catchment area (the state of North Carolina) and offers a variety of important perspectives and constituencies, including cancer survivors and caregivers, community and faith-based organizations, rural and urban areas, state and non-profit agencies, and under-represented minorities. These coordinated teams of advisors provide critical advice and guidance, both annually in the fall and ad-hoc as required, ensuring that LCCC most effectively set priorities and pursues objectives that promote basic, clinical, prevention and translational research at the Center. With careful planning and critical input from advisory groups, the Director initiated a new 5 year strategic planning process, reorganized operating committees, continued significant recruitment, launched new population-based studies, strengthened community outreach efforts, and expanded immunotherapy and GMP infrastructure.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA016086-45
Application #
10089822
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
1997-06-01
Project End
2025-11-30
Budget Start
2020-12-01
Budget End
2021-11-30
Support Year
45
Fiscal Year
2021
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Shao, Wenwei; Chen, Xiaojing; Samulski, Richard J et al. (2018) Inhibition of antigen presentation during AAV gene therapy using virus peptides. Hum Mol Genet 27:601-613
Gao, Yanzhe; Kardos, Jordan; Yang, Yang et al. (2018) The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells. Sci Rep 8:15304
Schaefer, Kristina N; Bonello, Teresa T; Zhang, Shiping et al. (2018) Supramolecular assembly of the beta-catenin destruction complex and the effect of Wnt signaling on its localization, molecular size, and activity in vivo. PLoS Genet 14:e1007339
Zuze, Takondwa; Painschab, Matthew S; Seguin, Ryan et al. (2018) Plasmablastic lymphoma in Malawi. Infect Agent Cancer 13:22
Wang, Jeremy R; Holt, James; McMillan, Leonard et al. (2018) FMLRC: Hybrid long read error correction using an FM-index. BMC Bioinformatics 19:50
Lee, Janie M; Abraham, Linn; Lam, Diana L et al. (2018) Cumulative Risk Distribution for Interval Invasive Second Breast Cancers After Negative Surveillance Mammography. J Clin Oncol 36:2070-2077
Shen, Hui; Shih, Juliann; Hollern, Daniel P et al. (2018) Integrated Molecular Characterization of Testicular Germ Cell Tumors. Cell Rep 23:3392-3406
Cousins, Emily M; Goldfarb, Dennis; Yan, Feng et al. (2018) Competitive Kinase Enrichment Proteomics Reveals that Abemaciclib Inhibits GSK3? and Activates WNT Signaling. Mol Cancer Res 16:333-344
Armstrong, Robin L; Penke, Taylor J R; Strahl, Brian D et al. (2018) Chromatin conformation and transcriptional activity are permissive regulators of DNA replication initiation in Drosophila. Genome Res 28:1688-1700
Hoadley, Katherine A; Yau, Christina; Hinoue, Toshinori et al. (2018) Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer. Cell 173:291-304.e6

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