COMMUNICATIONS FOR HEALTH APPLICATIONS AND INTERVENTIONS The Communications for Health Applications and Interventions (CHAI) SR provides tremendous value and service to the Center through its development of modern communication techniques for the range of implementation, clinical, prevention and control research. The services available include behavioral e- and m- health interventions, qualitative and software design services using adaptive technology. Services for faculty research projects include: responsive web application, device integration, geofencing, user experience (UX) and qualitative survey development. The SR was used by more than 30 faculty in fiscal year 2019 which represented 82% of the total users. CHAI requests $139,365 of a total operating budget of $959,660. The Center ensure cost-effectiveness and value to the membership through a sustained annual contribution of approximately $310,000. It is well integrated within the LCCC programs contributed to key studies including: ? PRO-PM: a qualitative study designed to understand patient, caregiver and provider perceptions on patient reported outcomes during chemotherapy. CHAI supported the research through creation of interview guides and conduct of over 100 one on one interviews with adult patients receiving chemotherapy, healthcare administrators, health service researchers, clinicians, and patient advocates across six cancer centers nationwide. ? PERC: a mixed method study to evaluate feasibility and acceptability of a web based, couple-focused intervention on prostate cancer symptom management, quality of life and psychosocial factors. CHAI hosted the web site and supported data collection though a built-in automatic tracking system for times logged in, time spent on site. ? COMET: a 5 year PCORI-funded project, will involve 1200 patients. The goal of the COMET (Comparison of Operative vs Monitoring and Endocrine Therapy) trial for low-risk ductal carcinoma in situ (DCIS). CHAI contributed to the creation of a responsive website that provide accessible, understandable, and evidence-based information about DCIS, treatment options, including the trade- offs of each treatment option. The 9 person CHAI SR includes experts in qualitative analysis, software development graphic design and project management. CHAI is directed by Deborah Tate, PhD a nationally recognized expert in communications and behavioral science. The SR uses multiple techniques to test the efficacy of e- or m- messaging and is careful to assess changes in communication usage for example that many in rural areas have restricted access to broadband yet higher penetration through mobile devices. Integration with Community Outreach and Engagement is key in the development of CHAI methods.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA016086-45
Application #
10089835
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
1997-06-01
Project End
2025-11-30
Budget Start
2020-12-01
Budget End
2021-11-30
Support Year
45
Fiscal Year
2021
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Guseman, Alex J; Perez Goncalves, Gerardo M; Speer, Shannon L et al. (2018) Protein shape modulates crowding effects. Proc Natl Acad Sci U S A 115:10965-10970
Xu, Bowen; Cai, Ling; Butler, Jason M et al. (2018) The Chromatin Remodeler BPTF Activates a Stemness Gene-Expression Program Essential for the Maintenance of Adult Hematopoietic Stem Cells. Stem Cell Reports 10:675-683
Gartlan, Kate H; Bommiasamy, Hemamalini; Paz, Katelyn et al. (2018) A critical role for donor-derived IL-22 in cutaneous chronic GVHD. Am J Transplant 18:810-820
Zhang, Yugen; Dittmer, Dirk P; Mieczkowski, Piotr A et al. (2018) RIG-I Detects Kaposi's Sarcoma-Associated Herpesvirus Transcripts in a RNA Polymerase III-Independent Manner. MBio 9:
Abida, Wassim; Sawyers, Charles L (2018) Targeting DNA Repair in Prostate Cancer. J Clin Oncol 36:1017-1019
Bigi, Rachele; Landis, Justin T; An, Hyowon et al. (2018) Epstein-Barr virus enhances genome maintenance of Kaposi sarcoma-associated herpesvirus. Proc Natl Acad Sci U S A 115:E11379-E11387
Liu, Jianfang; Lichtenberg, Tara; Hoadley, Katherine A et al. (2018) An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics. Cell 173:400-416.e11
Song, Lixin; Dunlap, Kaitlyn L; Tan, Xianming et al. (2018) Enhancing Survivorship Care Planning for Patients With Localized Prostate Cancer Using a Couple-Focused mHealth Symptom Self-Management Program: Protocol for a Feasibility Study. JMIR Res Protoc 7:e51
Laurberg, Tinne; Tramm, Trine; Nielsen, Torsten et al. (2018) Intrinsic subtypes and benefit from postmastectomy radiotherapy in node-positive premenopausal breast cancer patients who received adjuvant chemotherapy - results from two independent randomized trials. Acta Oncol 57:38-43
Zhu, Cheng; Beck, Matthew V; Griffith, Jack D et al. (2018) Large SOD1 aggregates, unlike trimeric SOD1, do not impact cell viability in a model of amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A 115:4661-4665

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