The Kaplan Comprehensive Cancer Center (KCCC) is the organization unit of NYU Medical Medical Center bringing together basic, epidemiologic, and clinical scientists to further the progress against cancer. Created in 1975, and now in its 23rd year of uninterrupted NCI core grant funding, the Center seeks five additional years of support. Recent changes in leadership have engendered the strengthening of the Center's programmatic structure, shared resource units and overall commitment by NYU Medical Center. Renewed institutional support to the KCCC is manifested in additional research and clinical space, and financial and organization status comparable to other academic departments; in addition, the new director, Franco M. Muggia, M.D., holds a concomitant appointment as Associate Dean of the medical school. Since assuming the director's position on July 1, 1997, Dr. Muggia has promoted a further integration of clinical and laboratory investigators within the outstanding basic science programs and has sought to strengthen translational research in environmental carcinogenesis and population science, based at the Nelson Institute of Environmental Medicine-a unique feature of this cancer center. Future plans embrace the vision of greater organ-oriented research through new programs in Breast and Genitourinary Cancer Research; another such study, Neuro-oncology, is presented as a developing program. Further reflecting the cross-fertilization of scientific disciplines, two new shared resources have been created: Population Genetics and Molecular Diagnostics. Blending the Center's overall expansion with selected organizational consolidation, we envision continued significant accomplishment through the 9 programs and 13 shared resources which foster and facilitate interchange among its 187 members. Their productivity promises to be reflected in cancer prevention and treatment efforts within the population we serve, and in research advances felt nationally and internationally.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA016087-21
Application #
2730148
Study Section
Subcommittee G - Education (NCI)
Program Officer
Silkensen, Shannon M
Project Start
1975-06-30
Project End
2000-11-30
Budget Start
1999-05-10
Budget End
1999-11-30
Support Year
21
Fiscal Year
1999
Total Cost
Indirect Cost
Name
New York University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016
Wong, Serre-Yu; Coffre, Maryaline; Ramanan, Deepshika et al. (2018) B Cell Defects Observed in Nod2 Knockout Mice Are a Consequence of a Dock2 Mutation Frequently Found in Inbred Strains. J Immunol 201:1442-1451
Burgess, Hannah M; Pourchet, Aldo; Hajdu, Cristina H et al. (2018) Targeting Poxvirus Decapping Enzymes and mRNA Decay to Generate an Effective Oncolytic Virus. Mol Ther Oncolytics 8:71-81
Diamond, Julie M; Vanpouille-Box, Claire; Spada, Sheila et al. (2018) Exosomes Shuttle TREX1-Sensitive IFN-Stimulatory dsDNA from Irradiated Cancer Cells to DCs. Cancer Immunol Res 6:910-920
Handler, Jesse; Cullis, Jane; Avanzi, Antonina et al. (2018) Pre-neoplastic pancreas cells enter a partially mesenchymal state following transient TGF-? exposure. Oncogene 37:4334-4342
Chen, Danqi; Fang, Lei; Mei, Shenglin et al. (2018) Erratum: ""Regulation of Chromatin Assembly and Cell Transformation by Formaldehyde Exposure in Human Cells"". Environ Health Perspect 126:019001
Fan, Xiaozhou; Peters, Brandilyn A; Jacobs, Eric J et al. (2018) Drinking alcohol is associated with variation in the human oral microbiome in a large study of American adults. Microbiome 6:59
Wadghiri, Youssef Z; Hoang, Dung Minh; Leporati, Anita et al. (2018) High-resolution Imaging of Myeloperoxidase Activity Sensors in Human Cerebrovascular Disease. Sci Rep 8:7687
Khodadadi-Jamayran, Alireza; Akgol-Oksuz, Betul; Afanasyeva, Yelena et al. (2018) Prognostic role of elevated mir-24-3p in breast cancer and its association with the metastatic process. Oncotarget 9:12868-12878
Wang, Shiyang; Liechty, Benjamin; Patel, Seema et al. (2018) Programmed death ligand 1 expression and tumor infiltrating lymphocytes in neurofibromatosis type 1 and 2 associated tumors. J Neurooncol 138:183-190
Nancy, Patrice; Siewiera, Johan; Rizzuto, Gabrielle et al. (2018) H3K27me3 dynamics dictate evolving uterine states in pregnancy and parturition. J Clin Invest 128:233-247

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