The Cancer Immunology Program is one of the longstanding components of the NYUCI, with 38 members from 9 Departments. This program has recently been expanded by the vigorous recruitment in Immunology conducted by the NYUCI and also the Department of Pathology, to new or newly renovated space. 12 faculty have been added to the Program in the past year;9 of these are new recruits brought to NYU School of Medicine from outstanding institutions such as Harvard, Stanford, Yale, UCSF, and others. Goals of the Cancer Immunology Program are: 1) to understand the biology of, more effectively diagnose, and develop treatments for neoplasms arising from cells of the lymphoid and myeloid system, 2) to understand the biology of tumor rejection, including the mechanisms used by tumors to evade the immune system;3) to effectively manipulate the immune system to promote immunotherapy of tumors. The program is subdivided into three thematic areas reflecting this tripartite mission. Members of this program collaborate extensively with other.NYUCI Programs, especially Growth Control, Breast Cancer, Neurooncology, and Melanoma. The Cancer Immunology Group has been highly productive, generating over 319 publications from 2002-2006 and has increased outside funding from $4.8 M in 2002 to $10.4 M in 2006. Total funding has increased from $7,128,048 to $11,674,122. Membership has increased from 17 to 38. Total publications for the past five years include 319 of which 4% are intra-programmatic and 15% are interprogrammatic.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016087-32
Application #
8376770
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
2013-02-28
Budget Start
2012-03-01
Budget End
2013-02-28
Support Year
32
Fiscal Year
2012
Total Cost
$31,051
Indirect Cost
$14,888
Name
New York University
Department
Type
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Pelzek, Adam J; Shopsin, Bo; Radke, Emily E et al. (2018) Human Memory B Cells Targeting Staphylococcus aureus Exotoxins Are Prevalent with Skin and Soft Tissue Infection. MBio 9:
Chiou, Kenneth L; Bergey, Christina M (2018) Methylation-based enrichment facilitates low-cost, noninvasive genomic scale sequencing of populations from feces. Sci Rep 8:1975
Jose, Cynthia C; Jagannathan, Lakshmanan; Tanwar, Vinay S et al. (2018) Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1. Mol Carcinog 57:794-806
Kourtis, Nikos; Lazaris, Charalampos; Hockemeyer, Kathryn et al. (2018) Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia. Nat Med 24:1157-1166
Formenti, Silvia C; Lee, Percy; Adams, Sylvia et al. (2018) Focal Irradiation and Systemic TGF? Blockade in Metastatic Breast Cancer. Clin Cancer Res 24:2493-2504
Snuderl, Matija; Kannan, Kasthuri; Pfaff, Elke et al. (2018) Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma. Nat Commun 9:2868
Stafford, James M; Lee, Chul-Hwan; Voigt, Philipp et al. (2018) Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma. Sci Adv 4:eaau5935
Lee, Chul-Hwan; Yu, Jia-Ray; Kumar, Sunil et al. (2018) Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin. Mol Cell 70:422-434.e6
Aiello, Nicole M; Maddipati, Ravikanth; Norgard, Robert J et al. (2018) EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration. Dev Cell 45:681-695.e4
Jung, Heekyung; Baek, Myungin; D'Elia, Kristen P et al. (2018) The Ancient Origins of Neural Substrates for Land Walking. Cell 172:667-682.e15

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