The Biomedical Informatics Shared Resource (BISR), a new Shared Resource of the NYU Cancer Institute (NYUCI), aims to provide to all members of the NYUCI rapid, high-quality, and cost-effective access to state of- the-art and novel bioinformatics and medical informatics methods, tools, infrastructure and expert consulting/analyses as well as broader collaborative science opportunities with highly qualified informatics faculty. The BISR is leveraged by the launching and development since 2009 of the NYU Center for Health Informatics and Bioinformatics (CHIBI), which provides BISR with: a large and high-impact faculty with expertise in all aspects of bioinformatics and medical informatics;a High Performance Computing Facility (HPC), 7 informatics methods development labs, a full range of educational activities, full informatics support of high throughput assays, and the Best Practices Integrative Informatics Consulting core (BPIC) BISR will offer the following informatics services, and resources: BISR faculty and staff embedded in the NYUCI;dedicated NYUCI member access consulting faculty within a branch of BPIC specifically devoted to cancer research;dedicated access to HPC resources;and unlimited access to automated data analysis pipelines, software, best practices, educational and training seminars, courses and materials. BISR enforces diverse and strict QA operating procedures;it has numerous fruitful interactions with most NYUCI shared resources. Finally, BISR implements cost-effective chargeback and usage policies, is comprehensively advised by a User Advisory, and reports directly to the NYUCI director and executive advisory committee.

Public Health Relevance

Modem cancer research critically depends on advanced computing for experimental data generation, storage, and interpretation. The Biomedical Informatics Shared Resource provides cutting-edge computing and data storage infrastructure, along with human expert consulting and collaboration to Cancer Institute members in support of all aspects of their research.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016087-34
Application #
8765183
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2014-03-01
Budget End
2015-02-28
Support Year
34
Fiscal Year
2014
Total Cost
$148,764
Indirect Cost
$60,997
Name
New York University
Department
Type
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Puranik, Amrutesh S; Leaf, Irina A; Jensen, Mark A et al. (2018) Kidney-resident macrophages promote a proangiogenic environment in the normal and chronically ischemic mouse kidney. Sci Rep 8:13948
Saint Fleur-Lominy, Shella; Maus, Mate; Vaeth, Martin et al. (2018) STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia. Cell Rep 24:3045-3060.e5
Cui, Xin; Morales, Renee-Tyler Tan; Qian, Weiyi et al. (2018) Hacking macrophage-associated immunosuppression for regulating glioblastoma angiogenesis. Biomaterials 161:164-178
Weng, Mao-Wen; Lee, Hyun-Wook; Park, Sung-Hyun et al. (2018) Aldehydes are the predominant forces inducing DNA damage and inhibiting DNA repair in tobacco smoke carcinogenesis. Proc Natl Acad Sci U S A 115:E6152-E6161
Burgess, Hannah M; Pourchet, Aldo; Hajdu, Cristina H et al. (2018) Targeting Poxvirus Decapping Enzymes and mRNA Decay to Generate an Effective Oncolytic Virus. Mol Ther Oncolytics 8:71-81
Wong, Serre-Yu; Coffre, Maryaline; Ramanan, Deepshika et al. (2018) B Cell Defects Observed in Nod2 Knockout Mice Are a Consequence of a Dock2 Mutation Frequently Found in Inbred Strains. J Immunol 201:1442-1451
Handler, Jesse; Cullis, Jane; Avanzi, Antonina et al. (2018) Pre-neoplastic pancreas cells enter a partially mesenchymal state following transient TGF-? exposure. Oncogene 37:4334-4342
Diamond, Julie M; Vanpouille-Box, Claire; Spada, Sheila et al. (2018) Exosomes Shuttle TREX1-Sensitive IFN-Stimulatory dsDNA from Irradiated Cancer Cells to DCs. Cancer Immunol Res 6:910-920
Fan, Xiaozhou; Peters, Brandilyn A; Jacobs, Eric J et al. (2018) Drinking alcohol is associated with variation in the human oral microbiome in a large study of American adults. Microbiome 6:59
Chen, Danqi; Fang, Lei; Mei, Shenglin et al. (2018) Erratum: ""Regulation of Chromatin Assembly and Cell Transformation by Formaldehyde Exposure in Human Cells"". Environ Health Perspect 126:019001

Showing the most recent 10 out of 1170 publications