The Biomedical Informatics Shared Resource (BISR), a new Shared Resource of the NYU Cancer Institute (NYUCI), aims to provide to all members of the NYUCI rapid, high-quality, and cost-effective access to state of- the-art and novel bioinformatics and medical informatics methods, tools, infrastructure and expert consulting/analyses as well as broader collaborative science opportunities with highly qualified informatics faculty. The BISR is leveraged by the launching and development since 2009 of the NYU Center for Health Informatics and Bioinformatics (CHIBI), which provides BISR with: a large and high-impact faculty with expertise in all aspects of bioinformatics and medical informatics;a High Performance Computing Facility (HPC), 7 informatics methods development labs, a full range of educational activities, full informatics support of high throughput assays, and the Best Practices Integrative Informatics Consulting core (BPIC) BISR will offer the following informatics services, and resources: BISR faculty and staff embedded in the NYUCI;dedicated NYUCI member access consulting faculty within a branch of BPIC specifically devoted to cancer research;dedicated access to HPC resources;and unlimited access to automated data analysis pipelines, software, best practices, educational and training seminars, courses and materials. BISR enforces diverse and strict QA operating procedures;it has numerous fruitful interactions with most NYUCI shared resources. Finally, BISR implements cost-effective chargeback and usage policies, is comprehensively advised by a User Advisory, and reports directly to the NYUCI director and executive advisory committee.
Modem cancer research critically depends on advanced computing for experimental data generation, storage, and interpretation. The Biomedical Informatics Shared Resource provides cutting-edge computing and data storage infrastructure, along with human expert consulting and collaboration to Cancer Institute members in support of all aspects of their research.
|Wang, Shiyang; Liechty, Benjamin; Patel, Seema et al. (2018) Programmed death ligand 1 expression and tumor infiltrating lymphocytes in neurofibromatosis type 1 and 2 associated tumors. J Neurooncol 138:183-190|
|Nancy, Patrice; Siewiera, Johan; Rizzuto, Gabrielle et al. (2018) H3K27me3 dynamics dictate evolving uterine states in pregnancy and parturition. J Clin Invest 128:233-247|
|Schulfer, Anjelique F; Battaglia, Thomas; Alvarez, Yelina et al. (2018) Intergenerational transfer of antibiotic-perturbed microbiota enhances colitis in susceptible mice. Nat Microbiol 3:234-242|
|Ge, Wenzhen; Clendenen, Tess V; Afanasyeva, Yelena et al. (2018) Circulating anti-Müllerian hormone and breast cancer risk: A study in ten prospective cohorts. Int J Cancer 142:2215-2226|
|Ruggles, Kelly V; Wang, Jincheng; Volkova, Angelina et al. (2018) Changes in the Gut Microbiota of Urban Subjects during an Immersion in the Traditional Diet and Lifestyle of a Rainforest Village. mSphere 3:|
|Winer, Benjamin Y; Shirvani-Dastgerdi, Elham; Bram, Yaron et al. (2018) Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection. Sci Transl Med 10:|
|Marié, Isabelle J; Chang, Hao-Ming; Levy, David E (2018) HDAC stimulates gene expression through BRD4 availability in response to IFN and in interferonopathies. J Exp Med 215:3194-3212|
|Gupta, Ankit; Xu, Jing; Lee, Shirley et al. (2018) Facile target validation in an animal model with intracellularly expressed monobodies. Nat Chem Biol 14:895-900|
|Lee, Hyun-Wook; Park, Sung-Hyun; Weng, Mao-Wen et al. (2018) E-cigarette smoke damages DNA and reduces repair activity in mouse lung, heart, and bladder as well as in human lung and bladder cells. Proc Natl Acad Sci U S A 115:E1560-E1569|
|Evensen, Nikki A; Madhusoodhan, P Pallavi; Meyer, Julia et al. (2018) MSH6 haploinsufficiency at relapse contributes to the development of thiopurine resistance in pediatric B-lymphoblastic leukemia. Haematologica 103:830-839|
Showing the most recent 10 out of 1170 publications