The Biomedical Informatics Shared Resource (BISR), a new Shared Resource of the NYU Cancer Institute (NYUCI), aims to provide to all members of the NYUCI rapid, high-quality, and cost-effective access to state of- the-art and novel bioinformatics and medical informatics methods, tools, infrastructure and expert consulting/analyses as well as broader collaborative science opportunities with highly qualified informatics faculty. The BISR is leveraged by the launching and development since 2009 of the NYU Center for Health Informatics and Bioinformatics (CHIBI), which provides BISR with: a large and high-impact faculty with expertise in all aspects of bioinformatics and medical informatics;a High Performance Computing Facility (HPC), 7 informatics methods development labs, a full range of educational activities, full informatics support of high throughput assays, and the Best Practices Integrative Informatics Consulting core (BPIC) BISR will offer the following informatics services, and resources: BISR faculty and staff embedded in the NYUCI;dedicated NYUCI member access consulting faculty within a branch of BPIC specifically devoted to cancer research;dedicated access to HPC resources;and unlimited access to automated data analysis pipelines, software, best practices, educational and training seminars, courses and materials. BISR enforces diverse and strict QA operating procedures;it has numerous fruitful interactions with most NYUCI shared resources. Finally, BISR implements cost-effective chargeback and usage policies, is comprehensively advised by a User Advisory, and reports directly to the NYUCI director and executive advisory committee.
Modem cancer research critically depends on advanced computing for experimental data generation, storage, and interpretation. The Biomedical Informatics Shared Resource provides cutting-edge computing and data storage infrastructure, along with human expert consulting and collaboration to Cancer Institute members in support of all aspects of their research.
|Taylor, Martin S; Altukhov, Ilya; Molloy, Kelly R et al. (2018) Dissection of affinity captured LINE-1 macromolecular complexes. Elife 7:|
|Bertrand, Anne; Baron, Maria; Hoang, Dung M et al. (2018) In Vivo Evaluation of Neuronal Transport in Murine Models of Neurodegeneration Using Manganese-Enhanced MRI. Methods Mol Biol 1779:527-541|
|Jung, Seungyoun; Allen, Naomi; Arslan, Alan A et al. (2018) Anti-Müllerian hormone and risk of ovarian cancer in nine cohorts. Int J Cancer 142:262-270|
|Wang, Sophia S; Carrington, Mary; Berndt, Sonja I et al. (2018) HLA Class I and II Diversity Contributes to the Etiologic Heterogeneity of Non-Hodgkin Lymphoma Subtypes. Cancer Res 78:4086-4096|
|Kirkling, Margaret E; Cytlak, Urszula; Lau, Colleen M et al. (2018) Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells. Cell Rep 23:3658-3672.e6|
|Gong, Yixiao; Lazaris, Charalampos; Sakellaropoulos, Theodore et al. (2018) Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries. Nat Commun 9:542|
|Hadi, Tarik; Boytard, Ludovic; Silvestro, Michele et al. (2018) Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells. Nat Commun 9:5022|
|Minton, Denise R; Nam, Minwoo; McLaughlin, Daniel J et al. (2018) Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs. Mol Cell 69:610-621.e5|
|Lim, Chae Ho; Sun, Qi; Ratti, Karan et al. (2018) Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing. Nat Commun 9:4903|
|Zhang, Yilong; Shao, Yongzhao (2018) Concordance measure and discriminatory accuracy in transformation cure models. Biostatistics 19:14-26|
Showing the most recent 10 out of 1170 publications