The Perlmutter Cancer Center (PCC) and NYU Langone Health are deeply committed to community service and engagement, as exemplified by our decades of community outreach and education and an extensive community and clinical partner network. The mission of the Community Outreach and Engagement Core (COE) is reduce the cancer burden and eliminate cancer disparities by disseminating and translating PCC research into policy and practice. COE focuses on the specific cancer burdens and disparities present in the diverse communities in our unique catchment area of Lower Manhattan, Brooklyn, Queens, Staten Island and Nassau County, Long Island. We also translate lessons learned from this microcosm of the future U.S. to have local, national and global impact on health policy. The Specific Ams of COE are:
Aim 1 : To identify and characterize the cancer burden and disparities in the PCC catchment area;
Aim 2 : To engage the PCC catchment area in precision medicine, cancer clinical trials, and cancer prevention and control research;
Aim 3 : To disseminate PCC research and evidence-based cancer prevention and care guidelines through culturally tailored approaches to mitigate longstanding cancer disparities;
and Aim 4 : To promote policy translation, evaluation and dissemination relevant to PCC catchment area communities in the U.S. and ultimately, the global community. The diversity of the PCC catchment area enables targeted research and engagement in precision medicine research initiatives involving at-risk subgroups across and within racial/ethnic minorities, many who are understudied and underserved and incur unique cancer disparities. Utilizing principles of community-based participatory research (CBPR), we will continue to engage community partners and implement patient navigator programs, which provide multi-dimensional, patient-centered approaches. By collaborating with community stakeholders, COE will ensure a culture of inclusiveness and equity in cancer prevention and population sciences research. Finally, we will disseminate evidence-based practices for preventing and addressing cancer disparities through culturally adapted tools and health information that is meaningful and relevant to underserved communities, including dissemination of best practices for community health worker and patient navigator strategies for cancer prevention and control. Our proposed strategies will support and enhance community outreach and recruitment into cancer clinical trials and precision medicine initiatives that will inform efforts to reduce cancer disparities in the U.S. population and worldwide. Future plans include a comprehensive new outreach effort, ?Stamp Out Cancer Brooklyn,? with the goal of bending the disparities curve for this young, highly diverse, county and significantly reducing cancer incidence in the future.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016087-39
Application #
9867651
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2020-03-01
Budget End
2021-02-28
Support Year
39
Fiscal Year
2020
Total Cost
Indirect Cost
Name
New York University
Department
Type
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Puranik, Amrutesh S; Leaf, Irina A; Jensen, Mark A et al. (2018) Kidney-resident macrophages promote a proangiogenic environment in the normal and chronically ischemic mouse kidney. Sci Rep 8:13948
Saint Fleur-Lominy, Shella; Maus, Mate; Vaeth, Martin et al. (2018) STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia. Cell Rep 24:3045-3060.e5
Cui, Xin; Morales, Renee-Tyler Tan; Qian, Weiyi et al. (2018) Hacking macrophage-associated immunosuppression for regulating glioblastoma angiogenesis. Biomaterials 161:164-178
Weng, Mao-Wen; Lee, Hyun-Wook; Park, Sung-Hyun et al. (2018) Aldehydes are the predominant forces inducing DNA damage and inhibiting DNA repair in tobacco smoke carcinogenesis. Proc Natl Acad Sci U S A 115:E6152-E6161
Burgess, Hannah M; Pourchet, Aldo; Hajdu, Cristina H et al. (2018) Targeting Poxvirus Decapping Enzymes and mRNA Decay to Generate an Effective Oncolytic Virus. Mol Ther Oncolytics 8:71-81
Wong, Serre-Yu; Coffre, Maryaline; Ramanan, Deepshika et al. (2018) B Cell Defects Observed in Nod2 Knockout Mice Are a Consequence of a Dock2 Mutation Frequently Found in Inbred Strains. J Immunol 201:1442-1451
Handler, Jesse; Cullis, Jane; Avanzi, Antonina et al. (2018) Pre-neoplastic pancreas cells enter a partially mesenchymal state following transient TGF-? exposure. Oncogene 37:4334-4342
Diamond, Julie M; Vanpouille-Box, Claire; Spada, Sheila et al. (2018) Exosomes Shuttle TREX1-Sensitive IFN-Stimulatory dsDNA from Irradiated Cancer Cells to DCs. Cancer Immunol Res 6:910-920
Fan, Xiaozhou; Peters, Brandilyn A; Jacobs, Eric J et al. (2018) Drinking alcohol is associated with variation in the human oral microbiome in a large study of American adults. Microbiome 6:59
Chen, Danqi; Fang, Lei; Mei, Shenglin et al. (2018) Erratum: ""Regulation of Chromatin Assembly and Cell Transformation by Formaldehyde Exposure in Human Cells"". Environ Health Perspect 126:019001

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