GENOME TECHNOLOGY CENTER (GTC) The Genome Technology Center (GTC) shared resource provides centralized, expert genomic services to all Perlmutter Cancer Center (PCC) investigators at NYU Langone Health (NYULH). Under the direction of Dr. Adriana Heguy, a recognized expert in genomic analysis, GTC is a state-of-the-art, high throughput, fast turnaround, fully equipped genomic facility, specializing in both short-read (Illumina) and long-read (PacBio, Oxford Nanopore Technologies) deep sequencing and sample preparation for a variety of applications including RNASeq, ChIPSeq, ATACSeq, bisulfite sequencing, single cell sequencing, chromatin conformation sequencing approaches, and many others. The GTC mission is to foster cross-institutional science by providing highly specialized support in a collaborative environment that results in successful grant applications and publications. GTC provides affordable access to technologically advanced services and instrumentation, and an educational environment for faculty, staff, fellows, and students in the PCC who are interested in learning how these technologies can advance their basic and clinical cancer research.
The Specific Aims of GTC are:
Aim 1) To provide expert genomic services;
Aim 2) To evaluate and implement novel genomic technology and thereby maintain state-of-the-art services;
Aim 3) To facilitate data sharing and storage through high performance computing secure servers;
Aim 4) To assist the CLIA-certified NGS laboratory in technology development and validation;
Aim 5) To educate and inform members of the PCC communities on genomic technologies and their utility for cancer research.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016087-40
Application #
10124313
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
1997-12-01
Project End
2024-02-29
Budget Start
2021-03-01
Budget End
2022-02-28
Support Year
40
Fiscal Year
2021
Total Cost
Indirect Cost
Name
New York University
Department
Type
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Chen, Danqi; Fang, Lei; Mei, Shenglin et al. (2018) Erratum: ""Regulation of Chromatin Assembly and Cell Transformation by Formaldehyde Exposure in Human Cells"". Environ Health Perspect 126:019001
Fan, Xiaozhou; Peters, Brandilyn A; Jacobs, Eric J et al. (2018) Drinking alcohol is associated with variation in the human oral microbiome in a large study of American adults. Microbiome 6:59
Wadghiri, Youssef Z; Hoang, Dung Minh; Leporati, Anita et al. (2018) High-resolution Imaging of Myeloperoxidase Activity Sensors in Human Cerebrovascular Disease. Sci Rep 8:7687
Khodadadi-Jamayran, Alireza; Akgol-Oksuz, Betul; Afanasyeva, Yelena et al. (2018) Prognostic role of elevated mir-24-3p in breast cancer and its association with the metastatic process. Oncotarget 9:12868-12878
Wang, Shiyang; Liechty, Benjamin; Patel, Seema et al. (2018) Programmed death ligand 1 expression and tumor infiltrating lymphocytes in neurofibromatosis type 1 and 2 associated tumors. J Neurooncol 138:183-190
Nancy, Patrice; Siewiera, Johan; Rizzuto, Gabrielle et al. (2018) H3K27me3 dynamics dictate evolving uterine states in pregnancy and parturition. J Clin Invest 128:233-247
Schulfer, Anjelique F; Battaglia, Thomas; Alvarez, Yelina et al. (2018) Intergenerational transfer of antibiotic-perturbed microbiota enhances colitis in susceptible mice. Nat Microbiol 3:234-242
Ge, Wenzhen; Clendenen, Tess V; Afanasyeva, Yelena et al. (2018) Circulating anti-Müllerian hormone and breast cancer risk: A study in ten prospective cohorts. Int J Cancer 142:2215-2226
Ruggles, Kelly V; Wang, Jincheng; Volkova, Angelina et al. (2018) Changes in the Gut Microbiota of Urban Subjects during an Immersion in the Traditional Diet and Lifestyle of a Rainforest Village. mSphere 3:
Winer, Benjamin Y; Shirvani-Dastgerdi, Elham; Bram, Yaron et al. (2018) Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection. Sci Transl Med 10:

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