Abstract

The Cancer Center Support (CORE) Grant supports the peer-funded research activities of The University of Texas M.D. Anderson Cancer Center in six broad programmatic areas: Biomathematics, Cell and Tumor Cell Biology, Genetics, Immunology, Experimental Therapeutic and Cancer Prevention and Control. It does so by providing support for the resources required for the continuation and the expansion of our diverse clinical and basic science research activities. The shared resources supported by the Core Grant include: Automated Cytometry and Cell Sorter Laboratory, Scanning Electron Microscopy Facility, Tissue Procurement and Banking Facility, Centralized Histopathology Laboratory, Research Animal Support Facility, Veterinary Resources Support Facility, Cancer Information Systems Resource, Biostatistical Resource Group, Clinical Trials Support, Synthetic Antigen Laboratory, and Macromolecular Synthesis and Analysis Facility. The Cancer Center Support (CORE) Grant also provides Developmental Funds to support new investigators with start-up funds or to initiate new shared facilities, and support for an external advisory committee for Planning and Evaluation.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016672-19
Application #
3101604
Study Section
Cancer Center Support Review Committee (CCS)
Project Start
1978-07-01
Project End
1997-06-30
Budget Start
1993-08-01
Budget End
1994-06-30
Support Year
19
Fiscal Year
1993
Total Cost
Indirect Cost

  Institution

Name
University of Texas MD Anderson Cancer Center
Department
Type
Other Domestic Higher Education
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030

  Publications

Knijnenburg, Theo A; Wang, Linghua; Zimmermann, Michael T et al. (2018) Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas. Cell Rep 23:239-254.e6
Gao, Qingsong; Liang, Wen-Wei; Foltz, Steven M et al. (2018) Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. Cell Rep 23:227-238.e3
Ikeda, Sadakatsu; Lim, Jordan S; Kurzrock, Razelle (2018) Analysis of Tissue and Circulating Tumor DNA by Next-Generation Sequencing of Hepatocellular Carcinoma: Implications for Targeted Therapeutics. Mol Cancer Ther 17:1114-1122
Ferrarotto, Renata; Cardnell, Robert; Su, Shirley et al. (2018) Poly ADP-ribose polymerase-1 as a potential therapeutic target in Merkel cell carcinoma. Head Neck 40:1676-1684
Sammour, Tarik; Malakorn, Songphol; Bednarski, Brian K et al. (2018) Oncological Outcomes After Robotic Proctectomy for Rectal Cancer: Analysis of a Prospective Database. Ann Surg 267:521-526
Burger, Jan A; Wiestner, Adrian (2018) Targeting B cell receptor signalling in cancer: preclinical and clinical advances. Nat Rev Cancer 18:148-167
Hobbs, Brian P; Chen, Nan; Lee, J Jack (2018) Controlled multi-arm platform design using predictive probability. Stat Methods Med Res 27:65-78
Gadhikar, Mayur A; Zhang, Jiexin; Shen, Li et al. (2018) CDKN2A/p16 Deletion in Head and Neck Cancer Cells Is Associated with CDK2 Activation, Replication Stress, and Vulnerability to CHK1 Inhibition. Cancer Res 78:781-797
Vial, Macarena R; O'Connell, Oisin J; Grosu, Horiana B et al. (2018) Diagnostic performance of endobronchial ultrasound-guided mediastinal lymph node sampling in early stage non-small cell lung cancer: A prospective study. Respirology 23:76-81
Housten, Ashley J; Lowenstein, Lisa M; Leal, Viola B et al. (2018) Responsiveness of a Brief Measure of Lung Cancer Screening Knowledge. J Cancer Educ 33:842-846

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