M. D. Anderson Cancer Center's (MDACC) planning and evaluation activities can be grouped into 4categories: external advisory board (EAB), program reviews, internal planning and review, and programdevelopment. External Advisory Board: MDACC has received support from the CCSG to fund an ExternalAdvisory Board (EAB) for the past 22 years. In this proposal, funds for planning and evaluation arerequested to permit MDACC to continue to convene annually this standing committee of 30 outstandingoutside scientific advisors to help plan and evaluate our programs, shared resources and institutionalresearch initiatives. The objectives of the EAB are to: review in-house research programs to evaluate theirproductivity, excellence, and applicability to institutional goals, identify potential gaps in the scientificactivities that might be crucial for development to achieve strategic research objectives, and suggest, at ahigh level, options to consider for closing these gaps, recommend approaches to develop new researchdirections, such as the three developing programs described here (Molecular Markers, Molecular Imaging,and Melanoma), and evaluate progress of these new programs, assist in recruiting faculty to the institutionby identifying appropriate candidates and evaluating the credentials of applicants for critical programs suchas the Trust, evaluate the level of collaboration between basic scientists, clinical scientists, and populationbasedinvestigators and recommend actions to appropriately enhance interactivity between these threeareas, and estimate the financial investment necessary for implementation of planned research initiatives.Program Reviews: In addition to the EAB, panels of external peer reviewers are convened to evaluate thequality and progress of selected CCSG programs. We expect to conduct 2-3 reviews annually.Internal Planning and Evaluation: Complementing external reviews are institutional internal researchplanning and review initiatives. A recent successful internal planning effort was the series of researchretreats led by Dr. Mendelsohn during 2006-07 to define major research direction for the next 10 years.Another initiative is the ad hoc program and shared resource reviews conducted by Dr. Bast, VP oftranslational research and cancer center co-director, Ms. Tektiridis, CCSG executive director, and others asappropriate to the circumstances, to monitor progress in addressing issues identified through external peerreviews, address issues identified in administrative and financial assessments, and to review internalprogram member and shared resource user feedback. Program Development: Currently, there are threeCCSG developing programs, Molecular Markers, Molecular Imaging, and Melanoma, reflective of MDACC'sresearch initiatives in these areas.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA016672-33
Application #
7695926
Study Section
Subcommittee G - Education (NCI)
Project Start
2008-08-28
Project End
2013-06-30
Budget Start
2008-08-28
Budget End
2009-06-30
Support Year
33
Fiscal Year
2008
Total Cost
$51,370
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Type
DUNS #
800772139
City
Houston
State
TX
Country
United States
Zip Code
77030
Korch, Christopher; Hall, Erin M; Dirks, Wilhelm G et al. (2018) Authentication of M14 melanoma cell line proves misidentification of MDA-MB-435 breast cancer cell line. Int J Cancer 142:561-572
Lee, Jong-Ho; Liu, Rui; Li, Jing et al. (2018) EGFR-Phosphorylated Platelet Isoform of Phosphofructokinase 1 Promotes PI3K Activation. Mol Cell 70:197-210.e7
Brown, Justin C; Troxel, Andrea B; Ky, Bonnie et al. (2018) Dose-response Effects of Aerobic Exercise Among Colon Cancer Survivors: A Randomized Phase II Trial. Clin Colorectal Cancer 17:32-40
Zhang, Hong; Wang, Yirong; Li, Jun et al. (2018) Biosynthetic energy cost for amino acids decreases in cancer evolution. Nat Commun 9:4124
Vilar-Compte, Diana; Shah, Dimpy P; Vanichanan, Jakapat et al. (2018) Influenza in patients with hematological malignancies: Experience at two comprehensive cancer centers. J Med Virol 90:50-60
Bambhroliya, Arvind; Van Wyhe, Renae D; Kumar, Swaminathan et al. (2018) Gene set analysis of post-lactational mammary gland involution gene signatures in inflammatory and triple-negative breast cancer. PLoS One 13:e0192689
Koay, Eugene J; Lee, Yeonju; Cristini, Vittorio et al. (2018) A Visually Apparent and Quantifiable CT Imaging Feature Identifies Biophysical Subtypes of Pancreatic Ductal Adenocarcinoma. Clin Cancer Res 24:5883-5894
Jain, N; Zhu, H; Khashab, T et al. (2018) Targeting nucleolin for better survival in diffuse large B-cell lymphoma. Leukemia 32:663-674
Parker, Patricia A; Peterson, Susan K; Shen, Yu et al. (2018) Prospective Study of Psychosocial Outcomes of Having Contralateral Prophylactic Mastectomy Among Women With Nonhereditary Breast Cancer. J Clin Oncol 36:2630-2638
Fathi, Amir T; Erba, Harry P; Lancet, Jeffrey E et al. (2018) A phase 1 trial of vadastuximab talirine combined with hypomethylating agents in patients with CD33-positive AML. Blood 132:1125-1133

Showing the most recent 10 out of 12418 publications