Abstract

of the Shared ResourceThe Animal Resources Center (ARC) provides a comprehensive, centralized animal care program in support oflaboratory animal research at St. Jude Children's Research Hospital. The ARC supports the research of 56Cancer Center members in five programs by providing specialized housing and animal care, diagnosticservices, regulatory compliance, rodent breeding colony management, cryopreservation services, training, andprofessional veterinary services related to laboratory animal medicine and science.ARC provides rodent barrier facilities for maintaining specific pathogen-free (SPF) rodents and containmentlaboratories for work with hazardous agents in support of cancer biology research. The services of the ARCShared Resource are crucial to the success of all Cancer Center investigators who need specialized housingand animal research technical services to meet the objectives of their research programs.The animal care program at St. Jude is fully accredited by the Association for the Assessment andAccreditation of Laboratory Animal Care, International. The last accreditation site visit was conducted August3-4, 2006. St. Jude is registered with the U.S Department of Agriculture (63-R-0007) as a research facility andhas an assurance statement (Assurance No. A3077-01) on file with the Office of Laboratory Animal Welfare atthe NIH.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA021765-30
Application #
7714151
Study Section
Special Emphasis Panel (ZCA1-RTRB-Z (O1))
Project Start
2008-06-14
Project End
2013-02-28
Budget Start
2008-06-14
Budget End
2009-02-28
Support Year
30
Fiscal Year
2008
Total Cost
$323,027
Indirect Cost

  Institution

Name
St. Jude Children's Research Hospital
Department
Type
DUNS #
067717892
City
Memphis
State
TN
Country
United States
Zip Code
38105

  Publications

Ferrolino, Mylene C; Mitrea, Diana M; Michael, J Robert et al. (2018) Compositional adaptability in NPM1-SURF6 scaffolding networks enabled by dynamic switching of phase separation mechanisms. Nat Commun 9:5064
Bjornard, Kari L; Gilchrist, Laura S; Inaba, Hiroto et al. (2018) Peripheral neuropathy in children and adolescents treated for cancer. Lancet Child Adolesc Health 2:744-754
Gibson, Todd M; Li, Chenghong; Armstrong, Gregory T et al. (2018) Perceptions of future health and cancer risk in adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Cancer 124:3436-3444
Yang, Kai; Blanco, Daniel Bastardo; Chen, Xiang et al. (2018) Metabolic signaling directs the reciprocal lineage decisions of ?? and ?? T cells. Sci Immunol 3:
Kumar, Rahul; Liu, Anthony P Y; Orr, Brent A et al. (2018) Advances in the classification of pediatric brain tumors through DNA methylation profiling: From research tool to frontline diagnostic. Cancer 124:4168-4180
Rusch, Michael; Nakitandwe, Joy; Shurtleff, Sheila et al. (2018) Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome. Nat Commun 9:3962
Luo, Yi; Shao, Lijian; Chang, Jianhui et al. (2018) M1 and M2 macrophages differentially regulate hematopoietic stem cell self-renewal and ex vivo expansion. Blood Adv 2:859-870
Peterson, Rachel K; Ashford, Jason M; Scott, Sarah M et al. (2018) Predicting parental distress among children newly diagnosed with craniopharyngioma. Pediatr Blood Cancer 65:e27287
Heitzer, Andrew M; Ashford, Jason M; Harel, Brian T et al. (2018) Computerized assessment of cognitive impairment among children undergoing radiation therapy for medulloblastoma. J Neurooncol :
Dove, Austin P; Manole, Bogdan-Alexandru; Wakefield, Daniel V et al. (2018) Managing local-regional failure in children with high-risk neuroblastoma: A single institution experience. Pediatr Blood Cancer 65:e27408

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