Abstract

of the Shared ResourceThe Animal Resources Center (ARC) provides a comprehensive, centralized animal care program in support oflaboratory animal research at St. Jude Children's Research Hospital. The ARC supports the research of 56Cancer Center members in five programs by providing specialized housing and animal care, diagnosticservices, regulatory compliance, rodent breeding colony management, cryopreservation services, training, andprofessional veterinary services related to laboratory animal medicine and science.ARC provides rodent barrier facilities for maintaining specific pathogen-free (SPF) rodents and containmentlaboratories for work with hazardous agents in support of cancer biology research. The services of the ARCShared Resource are crucial to the success of all Cancer Center investigators who need specialized housingand animal research technical services to meet the objectives of their research programs.The animal care program at St. Jude is fully accredited by the Association for the Assessment andAccreditation of Laboratory Animal Care, International. The last accreditation site visit was conducted August3-4, 2006. St. Jude is registered with the U.S Department of Agriculture (63-R-0007) as a research facility andhas an assurance statement (Assurance No. A3077-01) on file with the Office of Laboratory Animal Welfare atthe NIH.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA021765-30
Application #
7714151
Study Section
Special Emphasis Panel (ZCA1-RTRB-Z (O1))
Project Start
2008-06-14
Project End
2013-02-28
Budget Start
2008-06-14
Budget End
2009-02-28
Support Year
30
Fiscal Year
2008
Total Cost
$323,027
Indirect Cost

  Institution

Name
St. Jude Children's Research Hospital
Department
Type
DUNS #
067717892
City
Memphis
State
TN
Country
United States
Zip Code
38105

  Publications

Devine, Katie A; Mertens, Ann C; Whitton, John A et al. (2018) Factors associated with physical activity among adolescent and young adult survivors of early childhood cancer: A report from the childhood cancer survivor study (CCSS). Psychooncology 27:613-619
Matreyek, Kenneth A; Starita, Lea M; Stephany, Jason J et al. (2018) Multiplex assessment of protein variant abundance by massively parallel sequencing. Nat Genet 50:874-882
Hazlitt, Robert A; Min, Jaeki; Zuo, Jian (2018) Progress in the Development of Preventative Drugs for Cisplatin-Induced Hearing Loss. J Med Chem 61:5512-5524
Hoehn, Mary Ellen; Calderwood, Julie; Gannon, Edwin et al. (2018) Ocular complications in a young pediatric population following bone marrow transplantation. J AAPOS 22:102-106.e1
Zimmerman, Mark W; Liu, Yu; He, Shuning et al. (2018) MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification. Cancer Discov 8:320-335
Hammill, Jared T; Bhasin, Deepak; Scott, Daniel C et al. (2018) Discovery of an Orally Bioavailable Inhibitor of Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation. J Med Chem 61:2694-2706
Li, Yanfeng; Bakke, Jesse; Finkelstein, David et al. (2018) HNRNPH1 is required for rhabdomyosarcoma cell growth and survival. Oncogenesis 7:9
Khan, Raja B; Merchant, Thomas E; Sadighi, Zsila S et al. (2018) Prevalence, risk factors, and response to treatment for hypersomnia of central origin in survivors of childhood brain tumors. J Neurooncol 136:379-384
Ma, Xiaotu; Liu, Yu; Liu, Yanling et al. (2018) Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours. Nature 555:371-376
Broniscer, Alberto; Jia, Sujuan; Mandrell, Belinda et al. (2018) Phase 1 trial, pharmacokinetics, and pharmacodynamics of dasatinib combined with crizotinib in children with recurrent or progressive high-grade and diffuse intrinsic pontine glioma. Pediatr Blood Cancer 65:e27035

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