Abstract

A. Purpose and ObjectivesThis resource exists to provide investigators of the Cancer Center with access to expertise in flow cytometryand cell sorting. The facility is equipped with state-of-the-art instrumentation, and its staff is capable ofperforming a wide variety of experiments, for the analysis and separation of cell populations stained withfluorescent compounds. Flow cytometry and cell sorting continue to be essential for a wide variety of researchprograms at this Cancer Center, and open access to this facility for all investigators obviates the need forinvestigators to acquire the equipment, technology and experience individually. This facility has equipmentand reagents that can be flexibly configured and used to perform a very wide range of experiments, so as tomeet the varied needs of a large number of investigators.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA021765-30
Application #
7714161
Study Section
Special Emphasis Panel (ZCA1-RTRB-Z (O1))
Project Start
2008-06-14
Project End
2013-02-28
Budget Start
2008-06-14
Budget End
2009-02-28
Support Year
30
Fiscal Year
2008
Total Cost
$159,135
Indirect Cost

  Institution

Name
St. Jude Children's Research Hospital
Department
Type
DUNS #
067717892
City
Memphis
State
TN
Country
United States
Zip Code
38105

  Publications

Browne, Emily K; Zhou, Yinmei; Chemaitilly, Wassim et al. (2018) Changes in body mass index, height, and weight in children during and after therapy for acute lymphoblastic leukemia. Cancer 124:4248-4259
Ehrhardt, Matthew J; Mulrooney, Daniel A; Li, Chenghong et al. (2018) Neurocognitive, psychosocial, and quality-of-life outcomes in adult survivors of childhood non-Hodgkin lymphoma. Cancer 124:417-425
Ma, Xiaotu; Liu, Yu; Liu, Yanling et al. (2018) Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours. Nature 555:371-376
Broniscer, Alberto; Jia, Sujuan; Mandrell, Belinda et al. (2018) Phase 1 trial, pharmacokinetics, and pharmacodynamics of dasatinib combined with crizotinib in children with recurrent or progressive high-grade and diffuse intrinsic pontine glioma. Pediatr Blood Cancer 65:e27035
Stewart, Daniel P; Marada, Suresh; Bodeen, William J et al. (2018) Cleavage activates dispatched for Sonic Hedgehog ligand release. Elife 7:
Wang, Zhaoming; Wilson, Carmen L; Easton, John et al. (2018) Genetic Risk for Subsequent Neoplasms Among Long-Term Survivors of Childhood Cancer. J Clin Oncol 36:2078-2087
Watson, Edmond R; Brown, Nicholas G; Peters, Jan-Michael et al. (2018) Posing the APC/C E3 Ubiquitin Ligase to Orchestrate Cell Division. Trends Cell Biol :
Inskip, Peter D; Veiga, Lene H S; Brenner, Alina V et al. (2018) Hypothyroidism after Radiation Therapy for Childhood Cancer: A Report from the Childhood Cancer Survivor Study. Radiat Res 190:117-132
Huang, I-Chan; Jones, Conor M; Brinkman, Tara M et al. (2018) Development of the functional social network index for adolescent and young adult cancer survivors. Cancer 124:2220-2227
Diouf, Barthelemy; Lin, Wenwei; Goktug, Asli et al. (2018) Alteration of RNA Splicing by Small-Molecule Inhibitors of the Interaction between NHP2L1 and U4. SLAS Discov 23:164-173

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