Abstract

of Shared Resource The Cell and Tissue Imaging (CTI) represents the merger of two previous Shared Resources, the Scientific Imaging Shared Resource (SISR) and the Cell Microinjection and Live Cell Imaging Shared Resource (CMLCI) in view of their programmatic overlap. All description of future plans and services reflect this merger. However, for administrative convenience, the two shared resources are treated as separate entities in the portions of this proposal dealing with usage, charge backs etc. It is anticipated that the two Shared Resources will be operatively and administratively integrated in the next year. Both components of the CTI have added additional instrumentation and technologies in the last three years (e.g., Multiphoton Microscopy and Live cell/confocal imaging) to make it a vastly expanded shared resource compared to the last cycle. There were also personnel changes in the CTI during the last cycle.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA021765-34
Application #
8378664
Study Section
Special Emphasis Panel (ZCA1-RTRB-Z)
Project Start
Project End
2014-02-28
Budget Start
2012-03-01
Budget End
2013-02-28
Support Year
34
Fiscal Year
2012
Total Cost
$260,157
Indirect Cost
$105,288

  Institution

Name
St. Jude Children's Research Hospital
Department
Type
DUNS #
067717892
City
Memphis
State
TN
Country
United States
Zip Code
38105

  Publications

van Oosterwijk, Jolieke G; Buelow, Daelynn R; Drenberg, Christina D et al. (2018) Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia. J Clin Invest 128:369-380
Howell, Carrie R; Wilson, Carmen L; Ehrhardt, Matthew J et al. (2018) Clinical impact of sedentary behaviors in adult survivors of acute lymphoblastic leukemia: A report from the St. Jude Lifetime Cohort study. Cancer 124:1036-1043
Zamora, Anthony E; Crawford, Jeremy Chase; Thomas, Paul G (2018) Hitting the Target: How T Cells Detect and Eliminate Tumors. J Immunol 200:392-399
Zhong, Bo; Maharaj, Anil; Davis, Abigail et al. (2018) Development and validation of a sensitive LC MS/MS method for the measurement of the checkpoint kinase 1 inhibitor prexasertib and its application in a cerebral microdialysis study. J Pharm Biomed Anal 156:97-103
Upadhyaya, Santhosh A; Robinson, Giles W; Harreld, Julie H et al. (2018) Marked functional recovery and imaging response of refractory optic pathway glioma to BRAFV600E inhibitor therapy: a report of two cases. Childs Nerv Syst 34:605-610
Goldsby, Robert E; Stratton, Kayla L; Raber, Shannon et al. (2018) Long-term sequelae in survivors of childhood leukemia with Down syndrome: A childhood cancer survivor study report. Cancer 124:617-625
Howell, Carrie R; Krull, Kevin R; Partin, Robyn E et al. (2018) Randomized web-based physical activity intervention in adolescent survivors of childhood cancer. Pediatr Blood Cancer 65:e27216
Cherian, Milu T; Chai, Sergio C; Wright, William C et al. (2018) CINPA1 binds directly to constitutive androstane receptor and inhibits its activity. Biochem Pharmacol 152:211-223
Hoehn, Mary Ellen; Calderwood, Julie; Gannon, Edwin et al. (2018) Ocular complications in a young pediatric population following bone marrow transplantation. J AAPOS 22:102-106.e1
Devine, Katie A; Mertens, Ann C; Whitton, John A et al. (2018) Factors associated with physical activity among adolescent and young adult survivors of early childhood cancer: A report from the childhood cancer survivor study (CCSS). Psychooncology 27:613-619

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