Abstract

of the Shared Resource The Animal Resources Center (ARC) provides a comprehensive, centralized animal care program in support of laboratory animal research at St. Jude Children's Research Hospital. The ARC supports the research of 56 Cancer Center members in five programs by providing specialized housing and animal care, diagnostic services, regulatory compliance, rodent breeding colony management, cryopreservation services, training, and professional veterinary services related to laboratory animal medicine and science. ARC provides rodent barrier facilities for maintaining specific pathogen-free (SPF) rodents and containment laboratories for work with hazardous agents in support of cancer biology research. The services of the ARC Shared Resource are crucial to the success of all Cancer Center investigators who need specialized housing and animal research technical services to meet the objectives of their research programs. The animal care program at St. Jude is fully accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care, International. The last accreditation site visit was conducted August 3-4, 2006. St. Jude is registered with the U.S Department of Agriculture (63-R-0007) as a research facility and has an assurance statement (Assurance No. A3077-01) on file with the Office of Laboratory Animal Welfare at the NIH.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA021765-34S4
Application #
8637119
Study Section
Special Emphasis Panel (ZCA1-RTRB-Z)
Project Start
Project End
Budget Start
2012-03-01
Budget End
2013-02-28
Support Year
34
Fiscal Year
2013
Total Cost
$5,527,034
Indirect Cost
$2,368,729

  Institution

Name
St. Jude Children's Research Hospital
Department
Type
DUNS #
067717892
City
Memphis
State
TN
Country
United States
Zip Code
38105

  Publications

Shadrick, William R; Slavish, Peter J; Chai, Sergio C et al. (2018) Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors. Bioorg Med Chem 26:25-36
Ramsey, Laura B; Balis, Frank M; O'Brien, Maureen M et al. (2018) Consensus Guideline for Use of Glucarpidase in Patients with High-Dose Methotrexate Induced Acute Kidney Injury and Delayed Methotrexate Clearance. Oncologist 23:52-61
Churchman, Michelle L; Qian, Maoxiang; Te Kronnie, Geertruy et al. (2018) Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia. Cancer Cell 33:937-948.e8
Hatfield, M Jason; Binder, Randall J; Gannon, Rowan et al. (2018) Potent, Irreversible Inhibition of Human Carboxylesterases by Tanshinone Anhydrides Isolated from Salvia miltiorrhiza (""Danshen""). J Nat Prod 81:2410-2418
Vo, BaoHan T; Kwon, Jin Ah; Li, Chunliang et al. (2018) Mouse medulloblastoma driven by CRISPR activation of cellular Myc. Sci Rep 8:8733
Mandrell, Belinda N; Avent, Yvonne; Walker, Breya et al. (2018) In-home salivary melatonin collection: Methodology for children and adolescents. Dev Psychobiol 60:118-122
Drummond, Catherine J; Hanna, Jason A; Garcia, Matthew R et al. (2018) Hedgehog Pathway Drives Fusion-Negative Rhabdomyosarcoma Initiated From Non-myogenic Endothelial Progenitors. Cancer Cell 33:108-124.e5
Jones, Conor M; Baker, Justin N; Keesey, Rachel M et al. (2018) Importance ratings on patient-reported outcome items for survivorship care: comparison between pediatric cancer survivors, parents, and clinicians. Qual Life Res 27:1877-1884
Huang, I-Chan; Brinkman, Tara M; Mullins, Larry et al. (2018) Child symptoms, parent behaviors, and family strain in long-term survivors of childhood acute lymphoblastic leukemia. Psychooncology 27:2031-2038
Huang, I-Chan; Klosky, James L; Young, Chelsea M et al. (2018) Misclassification of self-reported smoking in adult survivors of childhood cancer. Pediatr Blood Cancer 65:e27240

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