The Behavioral and Field Research Core (BFRC) is designed to facilitate the integration of communication and behavioral research across the Institute including work in epidemiology, cancer prevention, clinical and developmental therapeutics, palliative care, and genetics. The BFRC is grouped in the Population Research Core Cluster along with the Epidemiology Research Core. The Core offers expertise in communication science and behavioral research methodologies; design and evaluation of evidence-based social and behavioral interventions (including social marketing as a systematic approach to population level behavior change); social network methodology and analysis; quality of life measurement utilizing the most appropriate instruments; ecological momentary assessment (EMA techniques provide methods by which a research participant can report on symptoms, affect, behavior, and cognitions proximal to the experience, and these reports are obtained many times throughout the study); electronic daily diaries (QOL continues to be a critical factor in developmental therapeutic trials); and community engagement research, particularly related to health disparities. The Core maintains an active network of community organization partnerships across the Institute's catchment area. Community partners participate in research advisory committees and community advisory committees, providing community perspective, input and facilitating access to the populations they serve. Through these partnerships, the Core facilitates community access for Institute researchers, thus serving to assist in the translation and dissemination of cancer research. Resources available through BFRC include real-time video recording and coding of clinical interactions (including equipment, software and expertise), access to an extensive video archive for communication and behavioral studies, geographical and population tracking/mapping capabilities, community research participant registries, access to comprehensive national datasets (e.g. HINTS), as well as an extensive bank of clinical and social/behavioral instruments and measures. The services provided by the BFRC have contributed to 32 peer-reviewed publications during the current review period. As an example, the BFRC provided all regulatory tasks, recruitment, data collection, video capture, post-production editing, and coding for Dr. Penner's (PSDR) work demonstrating the importance of recognizing and understanding how the distinct dynamics of racially concordant and discordant interactions affect medical encounters and outcomes, (Hagiwara N, Soc SciMed, 2013).

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA022453-34
Application #
8997275
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2016-02-01
Budget End
2016-11-30
Support Year
34
Fiscal Year
2016
Total Cost
$39,313
Indirect Cost
$13,674
Name
Wayne State University
Department
Type
DUNS #
001962224
City
Detroit
State
MI
Country
United States
Zip Code
48202
Chammaa, May; Malysa, Agnes; Redondo, Carlos et al. (2018) RUMI is a novel negative prognostic marker and therapeutic target in non-small-cell lung cancer. J Cell Physiol 233:9548-9562
Alsaab, Hashem O; Sau, Samaresh; Alzhrani, Rami M et al. (2018) Tumor hypoxia directed multimodal nanotherapy for overcoming drug resistance in renal cell carcinoma and reprogramming macrophages. Biomaterials 183:280-294
Mills, Anne M; Peres, Lauren C; Meiss, Alice et al. (2018) Targetable Immune Regulatory Molecule Expression in High-Grade Serous Ovarian Carcinomas in African American Women: A Study of PD-L1 and IDO in 112 Cases From the African American Cancer Epidemiology Study (AACES). Int J Gynecol Pathol :
Vaishampayan, Ulka N; Podgorski, Izabela; Heilbrun, Lance K et al. (2018) Biomarkers and Bone Imaging Dynamics Associated with Clinical Outcomes of Oral Cabozantinib Therapy in Metastatic Castrate-Resistant Prostate Cancer. Clin Cancer Res :
Sexton, Rachel E; Hachem, Ali H; Assi, Ali A et al. (2018) Metabotropic glutamate receptor-1 regulates inflammation in triple negative breast cancer. Sci Rep 8:16008
Campbell, Douglas H; Lund, Maria E; Nocon, Aline L et al. (2018) Detection of glypican-1 (GPC-1) expression in urine cell sediments in prostate cancer. PLoS One 13:e0196017
Saadat, Nadia; Liu, Fangchao; Haynes, Brittany et al. (2018) Nano-delivery of RAD6/Translesion Synthesis Inhibitor SMI#9 for Triple-negative Breast Cancer Therapy. Mol Cancer Ther 17:2586-2597
Cheriyan, Vino T; Alsaab, Hashem; Sekhar, Sreeja et al. (2018) A CARP-1 functional mimetic compound is synergistic with BRAF-targeting in non-small cell lung cancers. Oncotarget 9:29680-29697
Burl, Rayanne B; Ramseyer, Vanesa D; Rondini, Elizabeth A et al. (2018) Deconstructing Adipogenesis Induced by ?3-Adrenergic Receptor Activation with Single-Cell Expression Profiling. Cell Metab 28:300-309.e4
Dedigama-Arachchige, Pavithra M; Acharige, Nuwan P N; Pflum, Mary Kay H (2018) Identification of PP1-Gadd34 substrates involved in the unfolded protein response using K-BIPS, a method for phosphatase substrate identification. Mol Omics 14:121-133

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