The Research Pharmacy Shared Service (RPSS) is one of the founding core services for this Cancer Center Support grant. It is responsible for investigation cancer drug inventory and preparation for the Multi- disciplinary Clinics of the Arizona Cancer Center. Located in the clinic area of the first floor, the service prepares over 2,800 investigation agents yearly, facilitated through the funding of a pharmacy technician, Estelle Wesau. Robert Dorr, Ph.D., R.Ph. is funded at 10% and serves as director of the services. He oversees the technician and investigational drug logistics for the entire Center. In addition, Dr. Dorr also prepares samples of investigation topical of injectable formulations of new agents or repackages active and placebo dosages for double-blinded pilot clinical trials. The later service totaled six projects for drug formulation and three projects for double-blind repackaging, respectively. The repackaged investigational agents are primarily used in the Cancer Prevention and Control Research Program. The Research Pharmacy Shared Service provides investigational drug reconstitution for daily clinics in the Cancer Center and as such, swerves a variety of peer-reviewed clinical projects including those of the Southwest Oncology Group (SWOG) and the clinical trials of three large translational research program project grants: the Medical Oncology Program Project, the Colon Cancer Prevention Program Project, and the Chemoprevention of Skin Cancer Program Project. Private (drug company) or other investigational trials may use the service of a when-available charge-back basis with funds used to buy equipment (freezers, computer, infusion pumps, etc.) to enhance the overall service effort. However, federal funding for this service is crucial since there are no charges to patients for preparation of any investigational drug, as it is done to pay for pharmacy services with commercially-available drugs.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA023074-22S2
Application #
6217325
Study Section
Project Start
1999-07-01
Project End
2000-06-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
22
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Arizona
Department
Type
DUNS #
City
Tucson
State
AZ
Country
United States
Zip Code
85721
Stanton, Annette L; Wiley, Joshua F; Krull, Jennifer L et al. (2018) Cancer-related coping processes as predictors of depressive symptoms, trajectories, and episodes. J Consult Clin Psychol 86:820-830
Siyahian, Aida; Malik, Saad Ullah; Mushtaq, Adeela et al. (2018) Prophylaxis for Hepatitis B Virus Reactivation after Allogeneic Stem Cell Transplantation in the Era of Drug Resistance and Newer Antivirals: A Systematic Review and Meta-Analysis. Biol Blood Marrow Transplant 24:1483-1489
Sun, Virginia; Crane, Tracy E; Slack, Samantha D et al. (2018) Rationale, development, and design of the Altering Intake, Managing Symptoms (AIMS) dietary intervention for bowel dysfunction in rectal cancer survivors. Contemp Clin Trials 68:61-66
Sinharay, Sanhita; Randtke, Edward A; Howison, Christine M et al. (2018) Detection of Enzyme Activity and Inhibition during Studies in Solution, In Vitro and In Vivo with CatalyCEST MRI. Mol Imaging Biol 20:240-248
Wales, Jessica A; Chen, Cheng-Yu; Breci, Linda et al. (2018) Discovery of stimulator binding to a conserved pocket in the heme domain of soluble guanylyl cyclase. J Biol Chem 293:1850-1864
Hsu, Chiu-Hsieh; Yu, Mandi (2018) Cox regression analysis with missing covariates via nonparametric multiple imputation. Stat Methods Med Res :962280218772592
Agasid, Mark T; Wang, Xuemin; Huang, Yiding et al. (2018) Expression, purification, and electrophysiological characterization of a recombinant, fluorescent Kir6.2 in mammalian cells. Protein Expr Purif 146:61-68
Remeniuk, Bethany; King, Tamara; Sukhtankar, Devki et al. (2018) Disease modifying actions of interleukin-6 blockade in a rat model of bone cancer pain. Pain 159:684-698
Bell, Melanie L (2018) New guidance to improve sample size calculations for trials: eliciting the target difference. Trials 19:605
Lindeman, Leila R; Randtke, Edward A; High, Rachel A et al. (2018) A comparison of exogenous and endogenous CEST MRI methods for evaluating in vivo pH. Magn Reson Med 79:2766-2772

Showing the most recent 10 out of 1336 publications