The Arizona Cancer Center (ACC) Cytogenetics Shared Service provides genetic characterization of normal and malignant cells in support of ACC research and collaborations, such as those with the National Human Genome Research Institute. Services include karyotyping and detailed chromosome analysis using fluorescence in situ hybridization (FISH). These services identify genetic abnormalities for detailed study and are an important quality control for cell lines. A database for prior karyotypes and FISH results is maintained and allows this shared services to compare current and past results to detect potential contaminants and detect genetic """"""""drift"""""""" in selected cell lines. By interfacing these results with resources of the Tissue Cultured Shared Service, unique cell lines developed by the ACC and """"""""public"""""""" cell lines with specific genetic abnormalities can be identified and provided to ACC investigators. The Cytogenetic Shared Service is the only facility providing detailed chromosome characterization of malignant cell on the Arizona Health Sciences Campus.
| Augustus, Gaius J; Ellis, Nathan A (2018) Colorectal Cancer Disparity in African Americans: Risk Factors and Carcinogenic Mechanisms. Am J Pathol 188:291-303 |
| Daenthanasanmak, Anusara; Wu, Yongxia; Iamsawat, Supinya et al. (2018) PIM-2 protein kinase negatively regulates T cell responses in transplantation and tumor immunity. J Clin Invest 128:2787-2801 |
| Cox, Christopher M; Lu, Ruifeng; Salcin, Kaan et al. (2018) The Endosomal Protein Endotubin Is Required for Enterocyte Differentiation. Cell Mol Gastroenterol Hepatol 5:145-156 |
| Das, Lipsa; Gard, Jaime M C; Prekeris, Rytis et al. (2018) Novel Regulation of Integrin Trafficking by Rab11-FIP5 in Aggressive Prostate Cancer. Mol Cancer Res 16:1319-1331 |
| Demark-Wahnefried, Wendy; Schmitz, Kathryn H; Alfano, Catherine M et al. (2018) Weight management and physical activity throughout the cancer care continuum. CA Cancer J Clin 68:64-89 |
| ?aniewski, Pawe?; Barnes, Dominique; Goulder, Alison et al. (2018) Linking cervicovaginal immune signatures, HPV and microbiota composition in cervical carcinogenesis in non-Hispanic and Hispanic women. Sci Rep 8:7593 |
| Augustus, Gaius Julian; Roe, Denise J; Jacobs, Elizabeth T et al. (2018) Is increased colorectal screening effective in preventing distant disease? PLoS One 13:e0200462 |
| Vrba, Lukas; Futscher, Bernard W (2018) A suite of DNA methylation markers that can detect most common human cancers. Epigenetics 13:61-72 |
| McLamarrah, Tiffany A; Buster, Daniel W; Galletta, Brian J et al. (2018) An ordered pattern of Ana2 phosphorylation by Plk4 is required for centriole assembly. J Cell Biol 217:1217-1231 |
| Mannakee, Brian K; Balaji, Uthra; Witkiewicz, Agnieszka K et al. (2018) Sensitive and specific post-call filtering of genetic variants in xenograft and primary tumors. Bioinformatics 34:1713-1718 |
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