The Cancer Center at the University of California San Diego School of Medicine is 3 years old. Building upon a firm laboratory research base, a strong and rapidly expanding clinical research program has developed, utilizing both local and national trials. This has led to appointment of an Assistant Director to corrdinate the clinical cancer research program, chair the Center's Protocol Review Committee, and supervise the planned data management system. The basic research program has also grown in a number of areas, including studies of human tumors in athymic mice, tumor cell culture in serum-free medium, and development of monoclonal antibodies to lymphocyte subpopulations. Construction of the new Theodore Gildred Cancer Facility, which was funded jointly by an NCI grant and a community drive, began in February 1981. When the facility is completed in early 1983, it will house many of the Center's research programs as well as a combined oncology clinic. In the past year the University has greatly increased its fiscal and philosophical commitment to the Cancer Center. This includes providing salary support for the Director, planning new faculty positions with joint appointments to the Center and an academic department, stimulating the formation of a foundation which will raise research funds for the Center, providing increased adminstrative funds, and allocating future additional laboratory research space for the Center's use. The Cancer Center Core Support Grant currently supports shared resource laboratories with expertise in pharmacology, serum-free culture medium, athymic mice, surface markers, cytogenetics, radiobiology, radioiodination, and biostatistics. A new immunology shared resource is planned and developmental funds for new research projects are needed. The Center anticipates continued development and expansion in its varied basic research, clinical research and education programs.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA023100-09
Application #
3101707
Study Section
Cancer Center Support Grant Review Committee (CCS)
Project Start
1978-04-01
Project End
1991-11-30
Budget Start
1989-01-09
Budget End
1989-11-30
Support Year
9
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Hoffmann, Hanne M; Gong, Ping; Tamrazian, Anika et al. (2018) Transcriptional interaction between cFOS and the homeodomain-binding transcription factor VAX1 on the GnRH promoter controls Gnrh1 expression levels in a GnRH neuron maturation specific manner. Mol Cell Endocrinol 461:143-154
Liu, Xuxiang; Cao, Minghui; Palomares, Melanie et al. (2018) Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts. Breast Cancer Res 20:127
Huang, Justin K; Carlin, Daniel E; Yu, Michael Ku et al. (2018) Systematic Evaluation of Molecular Networks for Discovery of Disease Genes. Cell Syst 6:484-495.e5
Kalyanaraman, Hema; Schwaerzer, Gerburg; Ramdani, Ghania et al. (2018) Protein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes. Diabetes 67:607-623
Hartman, Sheri J; Marinac, Catherine R; Cadmus-Bertram, Lisa et al. (2018) Sedentary Behaviors and Biomarkers Among Breast Cancer Survivors. J Phys Act Health 15:1-6
Wu, Yan; Tamayo, Pablo; Zhang, Kun (2018) Visualizing and Interpreting Single-Cell Gene Expression Datasets with Similarity Weighted Nonnegative Embedding. Cell Syst 7:656-666.e4
Dow, Michelle; Pyke, Rachel M; Tsui, Brian Y et al. (2018) Integrative genomic analysis of mouse and human hepatocellular carcinoma. Proc Natl Acad Sci U S A 115:E9879-E9888
Que, Xuchu; Hung, Ming-Yow; Yeang, Calvin et al. (2018) Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature 558:301-306
Murzin, Vyacheslav L; Woods, Kaley; Moiseenko, Vitali et al. (2018) 4? plan optimization for cortical-sparing brain radiotherapy. Radiother Oncol 127:128-135
Norton, Jeffrey A; Kim, Teresa; Kim, Joseph et al. (2018) SSAT State-of-the-Art Conference: Current Surgical Management of Gastric Tumors. J Gastrointest Surg 22:32-42

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