The Cancer Symptom Control Program consists of 17 Participating Members, representing total peer-reviewed funding for $4.14 Million annual direct costs ($5.65 Million in total costs). During the last two years, its members were responsible for a total of 100 cancer-relevant, peer-reviewed publications, 29% of which were intra- and inter- programmatic collaborations. This Program, formerly called """"""""Palliative Care"""""""", is dedicated to research on the impact of cancer on human consciousness and sensory experience. It is comprised of members who are conduct highly interlocking studies on the consequences of cancer and its treatment on the quality of life of the patient. These examine pain, fatigue, anxiety, depression and sleep fragmentation, caused by cancer and how these can best be ameliorated to improve quality of life and satisfaction with medical care. The studies also examine the efficience of communications between doctors and their patients and the effect of ethnic and cultural characteristics of the patients of the subjective experience of the disease. This Program brings to bear both basic and clinical research on mitigating the physical and mental anguish associated with cancer. Of course, the cancer patients themselves are the main beneficiaries of this research on symptom control, but their families with severe illnesses. Members of this Program have developed a series of studiers highly specific to cancer patients in terms of: (1) cancer pain syndromes; (2) fatigue and sleep in cancer patients, and; (3) quality of life in cancer patients.
| Dow, Michelle; Pyke, Rachel M; Tsui, Brian Y et al. (2018) Integrative genomic analysis of mouse and human hepatocellular carcinoma. Proc Natl Acad Sci U S A 115:E9879-E9888 |
| Que, Xuchu; Hung, Ming-Yow; Yeang, Calvin et al. (2018) Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature 558:301-306 |
| Murzin, Vyacheslav L; Woods, Kaley; Moiseenko, Vitali et al. (2018) 4? plan optimization for cortical-sparing brain radiotherapy. Radiother Oncol 127:128-135 |
| Norton, Jeffrey A; Kim, Teresa; Kim, Joseph et al. (2018) SSAT State-of-the-Art Conference: Current Surgical Management of Gastric Tumors. J Gastrointest Surg 22:32-42 |
| Ikeda, Sadakatsu; Tsigelny, Igor F; Skjevik, Åge A et al. (2018) Next-Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma. Oncologist 23:586-593 |
| Buckley, Alexandra R; Ideker, Trey; Carter, Hannah et al. (2018) Exome-wide analysis of bi-allelic alterations identifies a Lynch phenotype in The Cancer Genome Atlas. Genome Med 10:69 |
| Parish, Austin J; Nguyen, Vi; Goodman, Aaron M et al. (2018) GNAS, GNAQ, and GNA11 alterations in patients with diverse cancers. Cancer 124:4080-4089 |
| Xu, Selene; Thompson, Wesley; Ancoli-Israel, Sonia et al. (2018) Cognition, quality-of-life, and symptom clusters in breast cancer: Using Bayesian networks to elucidate complex relationships. Psychooncology 27:802-809 |
| Tao, Li; Schwab, Richard B; San Miguel, Yazmin et al. (2018) Breast Cancer Mortality in Older and Younger Breast Cancer Patients in California. Cancer Epidemiol Biomarkers Prev : |
| Sagredo, Eduardo A; Blanco, Alejandro; Sagredo, Alfredo I et al. (2018) ADAR1-mediated RNA-editing of 3'UTRs in breast cancer. Biol Res 51:36 |
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