CANCER RESEARCH CAREER ENHANCEMENT AND RELATED ACTIVITIES ABSTRACT Training future cancer researchers across the science spectrum and providing a rich mentoring environment for faculty of diverse interests and backgrounds is central to realizing MCC?s goal of fostering high-impact discoveries that transform the prevention, detection, and treatment of cancer. MCC faculty participate in a pipeline of outstanding training programs and activities that enhance the skills of the current and the next generation of cancer researchers. These efforts are aimed at providing high-quality training that increase the ability to make novel discoveries about the biology of cancer, translate these into novel therapeutic strategies, and facilitate their application by MCC and community clinicians and health care workers. The goal of the MCC Cancer Research Career Enhancement and Related Activities (CRCERA) core is to attract talented individuals into the field of cancer research as early as possible (beginning with high school and extending through undergraduate, graduate/medical student, postgraduate/postdoctoral, faculty, and healthcare providers in our community), and to support and enhance the research skills and performance of each person pursuing a career in cancer research. The Core?s mission is to support trainees at all levels in their cancer-focused career by innovating in career enhancement activities. It also aims to attract and support a diverse and robust cancer research workforce throughout the San Diego area. CRCERA will accomplish these goals by pursuing the following Specific Aims: 1) To provide an easily accessible conduit for high school and undergraduate students, including underrepresented minorities, towards laboratory or clinical-based cancer research careers. 2) To provide multidisciplinary cancer research and training opportunities for graduate students, MD/PhD candidates, and medical students. 3) To provide career enhancement activities, funding support and mentorship for postgraduate fellows and all levels of faculty. 4) To provide professional development activities in cancer care for community health care partners. MCC?s approach to research education and training is based on a combination of: i) attracting talented individuals into the field by engaging them in cancer research starting even at the high school level; ii) providing a myriad of cancer research education and training opportunities in all the major disciplines that relate to the biology, prevention, detection, treatment of cancer; and to the quality of life of cancer patients; iii) offering formal degree programs at the undergraduate, graduate, and post-graduate levels in the basic, translational, population, and clinical sciences; iv) creating MCC- managed programs that reflect the center?s commitment to diversity and disparities research and to continuing education for community health care workers; and, v) partnering with consortium and other local institutional partners to create and sustain relevant cancer-focused research training and education opportunities. Specific strengths of the CRCERA core include strong regional training and educational partnerships and MCC?s absolute commitment to reach underserved minorities in the San Diego area.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of California, San Diego
La Jolla
United States
Zip Code
Singh, Siddharth; Loomba, Rohit (2018) Role of two-dimensional shear wave elastography in the assessment of chronic liver diseases. Hepatology 67:13-15
Hartman, Sheri J; Nelson, Sandahl H; Myers, Emily et al. (2018) Randomized controlled trial of increasing physical activity on objectively measured and self-reported cognitive functioning among breast cancer survivors: The memory & motion study. Cancer 124:192-202
Hoffmann, Hanne M; Gong, Ping; Tamrazian, Anika et al. (2018) Transcriptional interaction between cFOS and the homeodomain-binding transcription factor VAX1 on the GnRH promoter controls Gnrh1 expression levels in a GnRH neuron maturation specific manner. Mol Cell Endocrinol 461:143-154
Liu, Xuxiang; Cao, Minghui; Palomares, Melanie et al. (2018) Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts. Breast Cancer Res 20:127
Huang, Justin K; Carlin, Daniel E; Yu, Michael Ku et al. (2018) Systematic Evaluation of Molecular Networks for Discovery of Disease Genes. Cell Syst 6:484-495.e5
Kalyanaraman, Hema; Schwaerzer, Gerburg; Ramdani, Ghania et al. (2018) Protein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes. Diabetes 67:607-623
Hartman, Sheri J; Marinac, Catherine R; Cadmus-Bertram, Lisa et al. (2018) Sedentary Behaviors and Biomarkers Among Breast Cancer Survivors. J Phys Act Health 15:1-6
Wu, Yan; Tamayo, Pablo; Zhang, Kun (2018) Visualizing and Interpreting Single-Cell Gene Expression Datasets with Similarity Weighted Nonnegative Embedding. Cell Syst 7:656-666.e4
Dow, Michelle; Pyke, Rachel M; Tsui, Brian Y et al. (2018) Integrative genomic analysis of mouse and human hepatocellular carcinoma. Proc Natl Acad Sci U S A 115:E9879-E9888
Que, Xuchu; Hung, Ming-Yow; Yeang, Calvin et al. (2018) Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature 558:301-306

Showing the most recent 10 out of 862 publications