Abstract

Since January 1996, a scientific review committee (Clinical Cancer Research Committee?CCRC) and a Safety and Data Monitoring Committee (SDMC) have functioned at Norris Cotton Cancer Center. The CCRC reviews each new clinical trial protocol prior to Institutional Review Board (IRB) review, and the SDMC monitors safety and data integrity on a regular basis throughout the trial. Prior to IRB review, the NCCC Office of Clinical Research (OCR) submits the protocol to the CCRC. The CCRC is responsible for the scientific review of all new studies involving cancer patients or cancer prevention in human subjects. This assessment involves a review of all scientific aspects of the study, including the required safety and data monitoring plan. Once a protocol receives CCRC and IRB approval, the protocol is considered open for activation.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA023108-32
Application #
8015012
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2009-12-01
Budget End
2010-11-30
Support Year
32
Fiscal Year
2010
Total Cost
$49,363
Indirect Cost

  Institution

Name
Dartmouth College
Department
Type
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755

  Publications

Taylor, Vivien F; Li, Zhigang; Sayarath, Vicki et al. (2018) Author Correction: Distinct arsenic metabolites following seaweed consumption in humans. Sci Rep 8:4145
Soneji, Samir; Yang, JaeWon; Moran, Meghan Bridgid et al. (2018) Engagement with Online Tobacco Marketing Among Adolescents in the US: 2013-2014 to 2014-2015. Nicotine Tob Res :
Almiron Bonnin, D A; Havrda, M C; Lee, M C et al. (2018) Secretion-mediated STAT3 activation promotes self-renewal of glioma stem-like cells during hypoxia. Oncogene 37:1107-1118
Wilkins, Owen M; Titus, Alexander J; Salas, Lucas A et al. (2018) MicroRNA-Related Genetic Variants Associated with Survival of Head and Neck Squamous Cell Carcinoma. Cancer Epidemiol Biomarkers Prev :
Kettenbach, Arminja N; Schlosser, Kate A; Lyons, Scott P et al. (2018) Global assessment of its network dynamics reveals that the kinase Plk1 inhibits the phosphatase PP6 to promote Aurora A activity. Sci Signal 11:
Buist, Diana S M; Abraham, Linn; Lee, Christoph I et al. (2018) Breast Biopsy Intensity and Findings Following Breast Cancer Screening in Women With and Without a Personal History of Breast Cancer. JAMA Intern Med 178:458-468
Rosenthal, Meredith B; Colla, Carrie H; Morden, Nancy E et al. (2018) Overuse and insurance plan type in a privately insured population. Am J Manag Care 24:140-146
Allaway, Robert J; Wood, Matthew D; Downey, Sondra L et al. (2018) Exploiting mitochondrial and metabolic homeostasis as a vulnerability in NF1 deficient cells. Oncotarget 9:15860-15875
Soneji, Samir; Yang, JaeWon; Knutzen, Kristin E et al. (2018) Online Tobacco Marketing and Subsequent Tobacco Use. Pediatrics 141:
Everson, Todd M; Punshon, Tracy; Jackson, Brian P et al. (2018) Cadmium-Associated Differential Methylation throughout the Placental Genome: Epigenome-Wide Association Study of Two U.S. Birth Cohorts. Environ Health Perspect 126:017010

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