Abstract

Since January 1996, a scientific review committee (Clinical Cancer Research Committee?CCRC) and a Safety and Data Monitoring Committee (SDMC) have functioned at Norris Cotton Cancer Center. The CCRC reviews each new clinical trial protocol prior to Institutional Review Board (IRB) review, and the SDMC monitors safety and data integrity on a regular basis throughout the trial. Prior to IRB review, the NCCC Office of Clinical Research (OCR) submits the protocol to the CCRC. The CCRC is responsible for the scientific review of all new studies involving cancer patients or cancer prevention in human subjects. This assessment involves a review of all scientific aspects of the study, including the required safety and data monitoring plan. Once a protocol receives CCRC and IRB approval, the protocol is considered open for activation.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA023108-35
Application #
8463400
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
2014-11-30
Budget Start
2012-12-01
Budget End
2013-11-30
Support Year
35
Fiscal Year
2013
Total Cost
$40,924
Indirect Cost
$15,023

  Institution

Name
Dartmouth College
Department
Type
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755

  Publications

Thompson, Jeffrey A; Christensen, Brock C; Marsit, Carmen J (2018) Pan-Cancer Analysis Reveals Differential Susceptibility of Bidirectional Gene Promoters to DNA Methylation, Somatic Mutations, and Copy Number Alterations. Int J Mol Sci 19:
Brooks, J M; Titus, A J; Bruce, M L et al. (2018) Depression and Handgrip Strength Among U.S. Adults Aged 60 Years and Older from NHANES 2011-2014. J Nutr Health Aging 22:938-943
Marra, Kayla; LaRochelle, Ethan P; Chapman, M Shane et al. (2018) Comparison of Blue and White Lamp Light with Sunlight for Daylight-Mediated, 5-ALA Photodynamic Therapy, in vivo. Photochem Photobiol 94:1049-1057
Murad, Joana M; Graber, David J; Sentman, Charles L (2018) Advances in the use of natural receptor- or ligand-based chimeric antigen receptors (CARs) in haematologic malignancies. Best Pract Res Clin Haematol 31:176-183
Pierce, John P; Sargent, James D; Portnoy, David B et al. (2018) Association Between Receptivity to Tobacco Advertising and Progression to Tobacco Use in Youth and Young Adults in the PATH Study. JAMA Pediatr 172:444-451
Bazett, Mark; Costa, Amanda M; Bosiljcic, Momir et al. (2018) Harnessing innate lung anti-cancer effector functions with a novel bacterial-derived immunotherapy. Oncoimmunology 7:e1398875
Taylor, Vivien F; Li, Zhigang; Sayarath, Vicki et al. (2018) Author Correction: Distinct arsenic metabolites following seaweed consumption in humans. Sci Rep 8:4145
Soneji, Samir; Yang, JaeWon; Moran, Meghan Bridgid et al. (2018) Engagement with Online Tobacco Marketing Among Adolescents in the US: 2013-2014 to 2014-2015. Nicotine Tob Res :
Almiron Bonnin, D A; Havrda, M C; Lee, M C et al. (2018) Secretion-mediated STAT3 activation promotes self-renewal of glioma stem-like cells during hypoxia. Oncogene 37:1107-1118
Wilkins, Owen M; Titus, Alexander J; Salas, Lucas A et al. (2018) MicroRNA-Related Genetic Variants Associated with Survival of Head and Neck Squamous Cell Carcinoma. Cancer Epidemiol Biomarkers Prev :

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