Abstract

Since January 1996, a scientific review committee (Clinical Cancer Research Committee?CCRC) and a Safety and Data Monitoring Committee (SDMC) have functioned at Norris Cotton Cancer Center. The CCRC reviews each new clinical trial protocol prior to Institutional Review Board (IRB) review, and the SDMC monitors safety and data integrity on a regular basis throughout the trial. Prior to IRB review, the NCCC Office of Clinical Research (OCR) submits the protocol to the CCRC. The CCRC is responsible for the scientific review of all new studies involving cancer patients or cancer prevention in human subjects. This assessment involves a review of all scientific aspects of the study, including the required safety and data monitoring plan. Once a protocol receives CCRC and IRB approval, the protocol is considered open for activation.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA023108-35
Application #
8463400
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
2014-11-30
Budget Start
2012-12-01
Budget End
2013-11-30
Support Year
35
Fiscal Year
2013
Total Cost
$40,924
Indirect Cost
$15,023

  Institution

Name
Dartmouth College
Department
Type
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755

  Publications

Yang, Wei; Hosford, Sarah R; Traphagen, Nicole A et al. (2018) Autophagy promotes escape from phosphatidylinositol 3-kinase inhibition in estrogen receptor-positive breast cancer. FASEB J 32:1222-1235
Landon, Bruce E; Keating, Nancy L; Onnela, Jukka-Pekka et al. (2018) Patient-Sharing Networks of Physicians and Health Care Utilization and Spending Among Medicare Beneficiaries. JAMA Intern Med 178:66-73
Ghali, Fady; Celaya, Maria; Laviolette, Michael et al. (2018) Does Travel Time to a Radiation Facility Impact Patient Decision-Making Regarding Treatment for Prostate Cancer? A Study of the New Hampshire State Cancer Registry. J Rural Health 34 Suppl 1:s84-s90
Goodwin, Eileen; Gilman, Morgan S A; Wrapp, Daniel et al. (2018) Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation. Immunity 48:339-349.e5
Buckey, Jay C; Phillips, Scott D; Anderson, Allison P et al. (2018) Microgravity-induced ocular changes are related to body weight. Am J Physiol Regul Integr Comp Physiol 315:R496-R499
He, Xiaofei; Schifferdecker, Karen E; Ozanne, Elissa M et al. (2018) How Do Women View Risk-Based Mammography Screening? A Qualitative Study. J Gen Intern Med 33:1905-1912
Marra, Kayla; LaRochelle, Ethan P; Chapman, M Shane et al. (2018) Comparison of Blue and White Lamp Light with Sunlight for Daylight-Mediated, 5-ALA Photodynamic Therapy, in vivo. Photochem Photobiol 94:1049-1057
Thompson, Jeffrey A; Christensen, Brock C; Marsit, Carmen J (2018) Pan-Cancer Analysis Reveals Differential Susceptibility of Bidirectional Gene Promoters to DNA Methylation, Somatic Mutations, and Copy Number Alterations. Int J Mol Sci 19:
Brooks, J M; Titus, A J; Bruce, M L et al. (2018) Depression and Handgrip Strength Among U.S. Adults Aged 60 Years and Older from NHANES 2011-2014. J Nutr Health Aging 22:938-943
Bazett, Mark; Costa, Amanda M; Bosiljcic, Momir et al. (2018) Harnessing innate lung anti-cancer effector functions with a novel bacterial-derived immunotherapy. Oncoimmunology 7:e1398875

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