Abstract

Purdue University is committed to the development of a multidisciplinary program for experimental cancer research with focus on the elucidation of the biological and biochemical events involved in cell transformation as the basis for new approaches to the prevention, diagnosis and chemical therapy of cancer. Ours is a specialized Cancer Center whose primary objectives are to correlate and integrate existing programs in cancer research at Purdue University, to stimulate new research in selected areas, to contribute to advanced training in cancer research, and to develop interactions among Purdue researchers, local physicians, hospitals and clinics and cancer researchers at other universities and research laboratories within the State of Indiana. This request is for a continuation of partial support for the administrative functions and the shared resources and services provided by the center as well as for center development and planning activities.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA023168-11
Application #
3101730
Study Section
Cancer Center Support Grant Review Committee (CCS)
Project Start
1978-04-01
Project End
1989-03-31
Budget Start
1988-04-01
Budget End
1989-03-31
Support Year
11
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
Purdue University
Department
Type
Organized Research Units
DUNS #
072051394
City
West Lafayette
State
IN
Country
United States
Zip Code
47907

  Publications

Morman, Rosemary E; Schweickert, Patrick G; Konieczny, Stephen F et al. (2018) BATF regulates the expression of Nfil3, Wnt10a and miR155hg for efficient induction of antibody class switch recombination in mice. Eur J Immunol 48:1492-1505
Zhang, Zhuangzhuang; Cheng, Lijun; Li, Jie et al. (2018) Inhibition of the Wnt/?-Catenin Pathway Overcomes Resistance to Enzalutamide in Castration-Resistant Prostate Cancer. Cancer Res 78:3147-3162
Rangasamy, Loganathan; Chelvam, Venkatesh; Kanduluru, Ananda Kumar et al. (2018) New Mechanism for Release of Endosomal Contents: Osmotic Lysis via Nigericin-Mediated K+/H+ Exchange. Bioconjug Chem 29:1047-1059
Zhang, Hao; Zhang, Yanqiu; Zhu, Xiaoyun et al. (2018) DEAD Box Protein 5 Inhibits Liver Tumorigenesis by Stimulating Autophagy via Interaction with p62/SQSTM1. Hepatology :
Lee, Hyeon Jeong; Li, Jie; Vickman, Renee E et al. (2018) Cholesterol Esterification Inhibition Suppresses Prostate Cancer Metastasis by Impairing the Wnt/?-catenin Pathway. Mol Cancer Res 16:974-985
Bhandari, Pushpak; Novikova, Gloriia; Goergen, Craig J et al. (2018) Ultrasound beam steering of oxygen nanobubbles for enhanced bladder cancer therapy. Sci Rep 8:3112
Dhawan, Deepika; Hahn, Noah M; Ramos-Vara, José A et al. (2018) Naturally-occurring canine invasive urothelial carcinoma harbors luminal and basal transcriptional subtypes found in human muscle invasive bladder cancer. PLoS Genet 14:e1007571
Shinde, Aparna; Libring, Sarah; Alpsoy, Aktan et al. (2018) Autocrine Fibronectin Inhibits Breast Cancer Metastasis. Mol Cancer Res 16:1579-1589
Ghosh, Arun K; Ghosh, Koena; Brindisi, Margherita et al. (2018) Design, synthesis, X-ray studies, and biological evaluation of novel BACE1 inhibitors with bicyclic isoxazoline carboxamides as the P3 ligand. Bioorg Med Chem Lett 28:2605-2610
Thompson, Taylor J; Han, Bumsoo (2018) Analysis of adhesion kinetics of cancer cells on inflamed endothelium using a microfluidic platform. Biomicrofluidics 12:042215

Showing the most recent 10 out of 436 publications