Public Health Relevance

The loss-of-function analysis enabled by siRNA screening in Functional Genomics provides an important tool in the mechanistic understanding of gene products that contribute to normal and aberrant cell growth, as well as genes and pathways that modify the response (or resistance) of tumor cells to therapeutic agents. Future gain-of-function studies with cDNA overexpression will complement these results.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA030199-29
Application #
8181812
Study Section
Subcommittee G - Education (NCI)
Project Start
2010-09-22
Project End
2015-04-30
Budget Start
2010-09-22
Budget End
2011-04-30
Support Year
29
Fiscal Year
2010
Total Cost
$94,932
Indirect Cost
Name
Sanford-Burnham Medical Research Institute
Department
Type
DUNS #
020520466
City
La Jolla
State
CA
Country
United States
Zip Code
92037
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