The Center Director has the authority and responsibility to define the Center's annual and long-term priorities and activities. Senior Leadership, Program Leaders and Faculty are significant contributors in the planning and evaluation process, as are Internal Advisory Groups consisting of the Program Planning Group (PPG), the Shared Resources Team, and the Administrative Team. External Advisory Groups consisting of the Cancer Center's Scientific Advisory Board (CCSAB) and Advisor for the Cancer Center Administration provide advice and new perspectives on current activities and future directions. Faculty provide input to planning and evaluation activities through Annual Reviews, Annual Faculty Retreat, and monthly Program Meetings. In these meetings. Program Leaders summarize the outcome of PPG discussions and actively solicit faculty feedback. This enhances the communication of Center goals to the faculty in a timely manner, and actively incorporates faculty opinions as part of developing plans. The Shared Resources Team evaluates the services of the core facilities in monthly meetings that are open to all faculty, and makes recommendations about future service needs and directions, including potential new instrumentation. Based on these sources of input, the PPG formulates specific annual goals and long-term plans, and presents these goals to CCSAB each spring. In parallel. Cancer Center's Administrative Team identifies mechanisms via which Center members can support these goals, through incentives such as pilot grant funding, development of core facilities and new instrumentation, and recruitment of new collaborating faculty. Once the goals are set, PPG and its ad hoc Task Forces consisting of several faculty members, including Recruitment and Pilot Project Committees, are primary drivers for implementing the goals that bring to the Center new technologies, new areas of research, and opportunities for scientific collaborations. Approved goals are distributed to all faculty and discussed in subsequent Program and Center meetings, to encourage Center-wide participation via various incentive mechanisms described above, and to assure continuous and iterative feedback from faculty on Center activities. Funding in the total amount of $16,000 is requested for the costs associated with the External Advisory Group activities, which include annual CCSAB meeting and annual Center Administration review. $20,000 is requested for the Annual Faculty Retreat. Institutional funds will be utilized to cover Internal Advisory Group activities, including monthly PPG, Administrative Team and Shared Resources Team meetings, as well as monthly Program meetings and Seminar Series.

Public Health Relevance

A strong planning and evaluation structure will permit the Center to identify both short-term and long-term scientific goals, to monitor progress toward meeting goals, and to plan for the facilities and financial support needed to meet these goals, thereby maximizing the scientific environment, collaborations and productivity of the Cancer Center Investigators.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA030199-32
Application #
8473814
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
32
Fiscal Year
2013
Total Cost
$186,476
Indirect Cost
$100,416
Name
Sanford-Burnham Medical Research Institute
Department
Type
DUNS #
020520466
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Wonder, Emily; Simón-Gracia, Lorena; Scodeller, Pablo et al. (2018) Competition of charge-mediated and specific binding by peptide-tagged cationic liposome-DNA nanoparticles in vitro and in vivo. Biomaterials 166:52-63
Limpert, Allison S; Lambert, Lester J; Bakas, Nicole A et al. (2018) Autophagy in Cancer: Regulation by Small Molecules. Trends Pharmacol Sci 39:1021-1032
Fujita, Yu; Khateb, Ali; Li, Yan et al. (2018) Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis. Cell Rep 24:3296-3311.e6
Scully, Kathleen M; Lahmy, Reyhaneh; Signaevskaia, Lia et al. (2018) E47 Governs the MYC-CDKN1B/p27KIP1-RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16INK4A and Wild-Type p53. Cell Mol Gastroenterol Hepatol 6:181-198
Borlido, Joana; Sakuma, Stephen; Raices, Marcela et al. (2018) Nuclear pore complex-mediated modulation of TCR signaling is required for naïve CD4+ T cell homeostasis. Nat Immunol 19:594-605
Follis, Ariele Viacava; Llambi, Fabien; Kalkavan, Halime et al. (2018) Regulation of apoptosis by an intrinsically disordered region of Bcl-xL. Nat Chem Biol 14:458-465
Pathria, Gaurav; Scott, David A; Feng, Yongmei et al. (2018) Targeting the Warburg effect via LDHA inhibition engages ATF4 signaling for cancer cell survival. EMBO J 37:
Sun, Younguk; Chen, Bo-Rui; Deshpande, Aniruddha (2018) Epigenetic Regulators in the Development, Maintenance, and Therapeutic Targeting of Acute Myeloid Leukemia. Front Oncol 8:41
Ekanayake, Vindana; Nisan, Danielle; Ryzhov, Pavel et al. (2018) Lipoprotein Particle Formation by Proapoptotic tBid. Biophys J 115:533-542
Diez-Cuñado, Marta; Wei, Ke; Bushway, Paul J et al. (2018) miRNAs that Induce Human Cardiomyocyte Proliferation Converge on the Hippo Pathway. Cell Rep 23:2168-2174

Showing the most recent 10 out of 599 publications