CANCER EDUCATION & CAREER ENHANCEMENT The Jackson Laboratory (JAX) has established a unique Cancer Education & Career Enhancement (CECE) Core within The Jackson Laboratory Cancer Center (JAXCC). JAX has deep experience in educating future and early career scientists in genetics and genomics, effectively leveraging modular and scalable educational units. The CECE Core focuses this experience on developing a diverse pipeline of early career cancer researchers to maximize their potential for impact on challenges in cancer. Aligned with the institutional commitment to educating the external research community, the Core offers educational programs in cancer genomics and genetics for internal and external scientists at many career stages and from varied backgrounds. The CECE leverages the well-regarded education programs managed by JAX's Education team, including the historic Summer Student Program, the renowned cancer-related short courses and workshops, and The Whole Scientist career development program. Dr. Linda Hicke, JAX Vice President for Education, leads the CECE Core as its first JAXCC Associate Director for Cancer Education and Career Enhancement. The CECE team has deep expertise in curriculum development, course design, postgraduate training, clinical and continuing medical education, and online education. The CECE Core also leverages JAX cancer genomics and informatics resources, including the CLIA-certified Clinical Genomics Laboratory and the Clinical Knowledgebase informatics to build modular training resources in the translational space for basic research and clinical audiences. These have been effectively used in the JAXCC-led Maine Cancer Genomics Initiative (MCGI), which provides education on somatic cancer testing to the oncology community in Maine. The CECE partners with MCGI to offer new training opportunities for cancer-focused Early Career Researchers in the application and implications of clinical cancer genomic testing, and new continuing education opportunities for clinicians. The CECE Core serves learners from high school students to faculty and clinicians. Bringing existing programs that serve basic research, clinical, and educator audiences under the JAXCC umbrella allows the CECE Core to create coordinated, cancer-specific content that informs a broad spectrum of audiences at different stages in the scientific workforce pipeline, and recruits early stage trainees to cancer research laboratories. This is accomplished through three Specific Aims.
Aim 1 supports and encourages JAXCC researchers through mentorship and a continuum of cancer courses, workshops and online training tools that provide modular educational experiences to foster continuous, life-long learning.
Aim 2 provides education and career development opportunities to external early career cancer researchers.
Aim 3 enhances interactions between basic research trainees, faculty and Maine community clinicians, with the goals to inform all participants about principles and use of genomic information in clinical decision making.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
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Subcommittee H - Clinical Groups (NCI)
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Jackson Laboratory
Bar Harbor
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Ye, Fengdan; Jia, Dongya; Lu, Mingyang et al. (2018) Modularity of the metabolic gene network as a prognostic biomarker for hepatocellular carcinoma. Oncotarget 9:15015-15026
Kong, Yang; Zhao, Lihong; Charette, Jeremy R et al. (2018) An FRMD4B variant suppresses dysplastic photoreceptor lesions in models of enhanced S-cone syndrome and of Nrl deficiency. Hum Mol Genet 27:3340-3352
Wu, Te-Chia; Xu, Kangling; Martinek, Jan et al. (2018) IL1 Receptor Antagonist Controls Transcriptional Signature of Inflammation in Patients with Metastatic Breast Cancer. Cancer Res 78:5243-5258
Muscat, Andrea M; Wong, Nicholas C; Drummond, Katharine J et al. (2018) The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection. Oncotarget 9:7844-7858
Kohar, Vivek; Lu, Mingyang (2018) Role of noise and parametric variation in the dynamics of gene regulatory circuits. NPJ Syst Biol Appl 4:40
NĂ©bor, Danitza; Graber, Joel H; Ciciotte, Steven L et al. (2018) Mutant KLF1 in Adult Anemic Nan Mice Leads to Profound Transcriptome Changes and Disordered Erythropoiesis. Sci Rep 8:12793
Linn, Sarah C; Mustonen, Allison M; Silva, Kathleen A et al. (2018) Nail abnormalities identified in an ageing study of 30 inbred mouse strains. Exp Dermatol :
Hosur, Vishnu; Farley, Michelle L; Burzenski, Lisa M et al. (2018) ADAM17 is essential for ectodomain shedding of the EGF-receptor ligand amphiregulin. FEBS Open Bio 8:702-710
Becker, Timothy; Lee, Wan-Ping; Leone, Joseph et al. (2018) FusorSV: an algorithm for optimally combining data from multiple structural variation detection methods. Genome Biol 19:38
Wang, Qianghu; Hu, Baoli; Hu, Xin et al. (2018) Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment. Cancer Cell 33:152

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