Abstract

) The Monoclonal Antibody Shared Resource is housed in Wittson Hall (rooms 4003 and 4005). Since 1997, a BIACore instrument and associated protocols were introduced into the facility (WH4011). The purpose of this Shared Resource is to develop, produce and characterize monoclonal antibodies for investigators. To accomplish this end, a large repertoire of protocols, from animal work to purification of genetically engineered antibodies, have been developed. The Monoclonal Antibody Shared Resource also supports a BIOShared Resource to evaluate binding affinities of biological molecules.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA036727-16
Application #
6404380
Study Section
Subcommittee E - Prevention &Control (NCI)
Project Start
1995-08-28
Project End
2004-07-31
Budget Start
Budget End
Support Year
16
Fiscal Year
2000
Total Cost
Indirect Cost

  Institution

Name
University of Nebraska Medical Center
Department
Type
DUNS #
City
Omaha
State
NE
Country
United States
Zip Code
68198

  Publications

Huang, Yunlong; Li, Yuju; Zhang, Hainan et al. (2018) Zika virus propagation and release in human fetal astrocytes can be suppressed by neutral sphingomyelinase-2 inhibitor GW4869. Cell Discov 4:19
Kumar, Vinod; Kumar, Virender; Chaudhary, Amit Kumar et al. (2018) Impact of miRNA-mRNA Profiling and Their Correlation on Medulloblastoma Tumorigenesis. Mol Ther Nucleic Acids 12:490-503
Fan, Wei; Zhang, Wenting; Alshehri, Sameer et al. (2018) Increasing time on target: utilization of inhibitors of cysteine cathepsins to enhance the tumor retention of receptor-targeted agents. Chem Commun (Camb) 54:11268-11271
Baranovskiy, Andrey G; Siebler, Hollie M; Pavlov, Youri I et al. (2018) Iron-Sulfur Clusters in DNA Polymerases and Primases of Eukaryotes. Methods Enzymol 599:1-20
Ouellette, Scot P; Messerli, Parker R; Wood, Nicholas A et al. (2018) Characterization of Chlamydial Rho and the Role of Rho-Mediated Transcriptional Polarity during Interferon Gamma-Mediated Tryptophan Limitation. Infect Immun 86:
Robb, Caroline M; Kour, Smit; Contreras, Jacob I et al. (2018) Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy. Oncotarget 9:5216-5232
Souchek, Joshua J; Wojtynek, Nicholas E; Payne, William M et al. (2018) Hyaluronic acid formulation of near infrared fluorophores optimizes surgical imaging in a prostate tumor xenograft. Acta Biomater 75:323-333
Wipfler, Kristin; Cornish, Adam S; Guda, Chittibabu (2018) Comparative molecular characterization of typical and exceptional responders in glioblastoma. Oncotarget 9:28421-28433
Attri, Kuldeep S; Mehla, Kamiya; Shukla, Surendra K et al. (2018) Microscale Gene Expression Analysis of Tumor-Associated Macrophages. Sci Rep 8:2408
Saxena, Ashima; Belinskaya, Tatyana; Schopfer, Lawrence M et al. (2018) Characterization of butyrylcholinesterase from porcine milk. Arch Biochem Biophys 652:38-49

Showing the most recent 10 out of 1372 publications