Abstract

) The Monoclonal Antibody Shared Resource is housed in Wittson Hall (rooms 4003 and 4005). Since 1997, a BIACore instrument and associated protocols were introduced into the facility (WH4011). The purpose of this Shared Resource is to develop, produce and characterize monoclonal antibodies for investigators. To accomplish this end, a large repertoire of protocols, from animal work to purification of genetically engineered antibodies, have been developed. The Monoclonal Antibody Shared Resource also supports a BIOShared Resource to evaluate binding affinities of biological molecules.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA036727-17
Application #
6492803
Study Section
Subcommittee E - Prevention &Control (NCI)
Project Start
2001-08-20
Project End
2002-07-31
Budget Start
Budget End
Support Year
17
Fiscal Year
2001
Total Cost
Indirect Cost

  Institution

Name
University of Nebraska Medical Center
Department
Type
DUNS #
City
Omaha
State
NE
Country
United States
Zip Code
68198

  Publications

Neilsen, Beth K; Chakraborty, Binita; McCall, Jamie L et al. (2018) WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage. BMC Cancer 18:673
Schopfer, Lawrence M; Lockridge, Oksana (2018) Chlorpyrifos oxon promotes tubulin aggregation via isopeptide cross-linking between diethoxyphospho-Lys and Glu or Asp: Implications for neurotoxicity. J Biol Chem 293:13566-13577
Baranovskiy, Andrey G; Duong, Vincent N; Babayeva, Nigar D et al. (2018) Activity and fidelity of human DNA polymerase ? depend on primer structure. J Biol Chem 293:6824-6843
Khadge, Saraswoti; Sharp, John Graham; Thiele, Geoffrey M et al. (2018) Dietary omega-3 and omega-6 polyunsaturated fatty acids modulate hepatic pathology. J Nutr Biochem 52:92-102
Kuss, Mitchell; Kim, Jiyoung; Qi, Dianjun et al. (2018) Effects of tunable, 3D-bioprinted hydrogels on human brown adipocyte behavior and metabolic function. Acta Biomater 71:486-495
Ingersoll, Matthew A; Chou, Yu-Wei; Lin, Jamie S et al. (2018) p66Shc regulates migration of castration-resistant prostate cancer cells. Cell Signal 46:1-14
Svechkarev, Denis; Kyrychenko, Alexander; Payne, William M et al. (2018) Development of colloidally stable carbazole-based fluorescent nanoaggregates. J Photochem Photobiol A Chem 352:55-64
Ambardekar, Vishakha V; Wakaskar, Rajesh R; Ye, Zhen et al. (2018) Complexation of Chol-DsiRNA in place of Chol-siRNA greatly increases the duration of mRNA suppression by polyplexes of PLL(30)-PEG(5K) in primary murine syngeneic breast tumors after i.v. administration. Int J Pharm 543:130-138
Tian, Tian; Bi, Chengfeng; Hein, Ashley L et al. (2018) Rac1 is a novel therapeutic target in mantle cell lymphoma. Blood Cancer J 8:17
Saxena, Sugandha; Purohit, Abhilasha; Varney, Michelle L et al. (2018) Semaphorin-5A maintains epithelial phenotype of malignant pancreatic cancer cells. BMC Cancer 18:1283

Showing the most recent 10 out of 1372 publications