Abstract

) The Protocol Review and Monitoring System (Scientific Review Committee - SRC) of the UNMC Eppley Cancer Center was formed in 1996. In September of 1997 the Chancellor of UNMC mandated that all cancer-related protocols be formally reviewed and approved by the SRC prior to being approved for accrual by the Institutional Review Board. The SRC also reviews all previously existing active cancer protocols for formal SRC approval prior to receiving renewal approval by the IRB. The SRC performs annual review of all cancer-related protocols. The Committee also reviews changes to investigator initiated or industry sponsored protocols before continued accrual can occur. The SRC has the authority to terminate cancer protocols under specific guidelines. The SRC meets monthly at least ten days prior to the IRB meeting. Expedited SRC review requests are coordinated through the SRC chair. The SRC reviewed 140 cancer-related protocols in 1998. The SRC is committed to peer reviewed clinical cancer research.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA036727-18
Application #
6654567
Study Section
Subcommittee E - Prevention &Control (NCI)
Project Start
2002-08-01
Project End
2003-07-31
Budget Start
Budget End
Support Year
18
Fiscal Year
2002
Total Cost
Indirect Cost

  Institution

Name
University of Nebraska Medical Center
Department
Type
DUNS #
City
Omaha
State
NE
Country
United States
Zip Code
68198

  Publications

Won, Harim I; Schulze, Thomas T; Clement, Emalie J et al. (2018) De novo Assembly of the Burying Beetle Nicrophorus orbicollis (Coleoptera: Silphidae) Transcriptome Across Developmental Stages with Identification of Key Immune Transcripts. J Genomics 6:41-52
Zhou, Jiuli; Zeng, Yongji; Cui, Lian et al. (2018) Zyxin promotes colon cancer tumorigenesis in a mitotic phosphorylation-dependent manner and through CDK8-mediated YAP activation. Proc Natl Acad Sci U S A 115:E6760-E6769
Das, Binita; Neilsen, Beth K; Fisher, Kurt W et al. (2018) A Functional Signature Ontology (FUSION) screen detects an AMPK inhibitor with selective toxicity toward human colon tumor cells. Sci Rep 8:3770
Qazi, Asif Khurshid; Siddiqui, Jawed A; Jahan, Rahat et al. (2018) Emerging therapeutic potential of graviola and its constituents in cancers. Carcinogenesis 39:522-533
Hsu, Alice H; Lum, Michelle A; Shim, Kang-Sup et al. (2018) Crosstalk between PKC? and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium. Cell Rep 24:655-669
Svechkarev, Denis; Sadykov, Marat R; Bayles, Kenneth W et al. (2018) Ratiometric Fluorescent Sensor Array as a Versatile Tool for Bacterial Pathogen Identification and Analysis. ACS Sens 3:700-708
Contreras, Jacob I; Robb, Caroline M; King, Hannah M et al. (2018) Chemical Genetic Screens Identify Kinase Inhibitor Combinations that Target Anti-Apoptotic Proteins for Cancer Therapy. ACS Chem Biol 13:1148-1152
Qi, Bowen; Crawford, Ayrianne J; Wojtynek, Nicholas E et al. (2018) Indocyanine green loaded hyaluronan-derived nanoparticles for fluorescence-enhanced surgical imaging of pancreatic cancer. Nanomedicine 14:769-780
Berger, Ann M; Kupzyk, Kevin A; Djalilova, Dilorom M et al. (2018) Breast Cancer Collaborative Registry informs understanding of factors predicting sleep quality. Support Care Cancer :
Svechkarev, Denis; Mohs, Aaron M (2018) Organic fluorescent dye-based nanomaterials: Advances in the rational design for imaging and sensing applications. Curr Med Chem :

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