RESEARCH INFORMATICS SHARED RESOURCE ABSTRACT The Research Informatics (RI) Shared Resource, established in 1995, provides Cancer Center members state- of-the-art software engineering, database design, and application and web development, as well as cutting- edge expertise in natural language processing, system design, data mining, and electronic data capture systems. Huntsman Cancer Institute (HCI) covers a majority of the costs of this stable, integrated team of computer professionals, enabling their allocation to the ongoing and new initiatives of highest importance to the cancer mission; priorities are determined by the HCI Director's Cabinet. Samir Courdy, BS, MBA, an accomplished computer scientist with expertise in software engineering and development of large-scale software systems, has directed the RI Shared Resource since 2006 and has managed all software development since 2000. Ms. Cindy Spigle, associate director of the RI Resource since 2011, is responsible for daily operations and assists Mr. Courdy in management. To achieve its goals, the RI Shared Resource provides computing infrastructure, hardware equipment, and services, including the latest advances in front-end graphical user interface (GUI) technologies and secure backend database engines and persistence layers. The RI Shared Resource has developed applications and databases for several other HCI-managed Shared Resources, including High-Throughput Genomics and Bioinformatic Analysis, Genetic Counseling, Biorepository and Molecular Pathology, and the Utah Population Database. The RI Shared Resource supports all four of the Cancer Center's Research Programs with the many software suites the team designs, builds, and supports. These include comprehensive suites of software applications for Cancer Clinical Research (CCR); Biospecimen Management and Annotation (itBioPath); a microarray and next-generation sequencing Laboratory Information Management System (LIMS) and experiment analysis and annotation suite (GNomEx); and a drug/chemical screening annotation and management suite (CSAM). CCR, itBioPath, and GNomEx are integrated systems providing genotype and phenotype associations for research. As software development is beyond the budget of most individual researchers, the RI Shared Resource adds important value to the Cancer Center by enabling a wide variety of researchers to utilize customized software tools without substantial financial investments. The Resource also provides cost savings to researchers by obtaining grant and institutional support to help offset software development costs. In 2013, use of the RI Shared Resource by Cancer Center members with peer-reviewed funding exceeded 57%, while the CCSG budget request is only 6% ($123,370) of the total proposed budget.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
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Study Section
Subcommittee I - Transistion to Independence (NCI)
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Ptak, Krzysztof
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University of Utah
Salt Lake City
United States
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Trott, Daniel W; Henson, Grant D; Ho, Mi H T et al. (2018) Age-related arterial immune cell infiltration in mice is attenuated by caloric restriction or voluntary exercise. Exp Gerontol 109:99-107
Wu, Yelena P; Parsons, Bridget G; Mooney, Ryan et al. (2018) Barriers and Facilitators to Melanoma Prevention and Control Behaviors Among At-Risk Children. J Community Health 43:993-1001
Zabriskie, Matthew S; Antelope, Orlando; Verma, Anupam R et al. (2018) A novel AGGF1-PDGFRb fusion in pediatric T-cell acute lymphoblastic leukemia. Haematologica 103:e87-e91
Wolff, Roger K; Hoffman, Michael D; Wolff, Erica C et al. (2018) Mutation analysis of adenomas and carcinomas of the colon: Early and late drivers. Genes Chromosomes Cancer 57:366-376
Hellwig, Sabine; Nix, David A; Gligorich, Keith M et al. (2018) Automated size selection for short cell-free DNA fragments enriches for circulating tumor DNA and improves error correction during next generation sequencing. PLoS One 13:e0197333
Fleming, Aaron M; Zhu, Judy; Ding, Yun et al. (2018) Human DNA Repair Genes Possess Potential G-Quadruplex Sequences in Their Promoters and 5'-Untranslated Regions. Biochemistry 57:991-1002
Mollaoglu, Gurkan; Jones, Alex; Wait, Sarah J et al. (2018) The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment. Immunity 49:764-779.e9
Martin, Christopher; Leiser, Claire L; O'Neil, Brock et al. (2018) Familial Cancer Clustering in Urothelial Cancer: A Population-Based Case-Control Study. J Natl Cancer Inst 110:527-533
Sorenson, Reed S; Deshotel, Malia J; Johnson, Katrina et al. (2018) Arabidopsis mRNA decay landscape arises from specialized RNA decay substrates, decapping-mediated feedback, and redundancy. Proc Natl Acad Sci U S A 115:E1485-E1494
Polanco, Edward R; Western, Nicholas; Zangle, Thomas A (2018) Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics. J Vis Exp :

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