The Flow Cytometry (FACS) Shared Resource assists Cancer Center members in performing cell sorting and fluorescence quantification using flow cytometry. The Shared Resource consists of two flow cytometers-a Coulter Epics Elite ESP flow cytometer/cell sorter and an automated benchtop Becton Dickinson FACS Caliber flow cytometer-and a full time technician. It is supervised by Dr. Scott Lowe (Associate Professor) and Ms. Linda Rogers (Senior Research Associate), and is operated by Ms. Klara Velinzon (Research Technician). The Facility is used by a large number of Cancer Center investigators for a variety of research procedures, ranging from sorting of specific cell types within complex populations to more routine fluorescence quantification. The research assistance provided by the FACS Shared Resource is essential for the cancer research conducted in the CSHL Cancer Center, and helps to integrate our research programs. We continue to request support for fixed costs of this faculty. Because fixed, central costs are a large population of the total costs, the Cancer Center Support Grant is absolutely essential for this Shared Resource and for the research it allows.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA045508-14
Application #
6348963
Study Section
Project Start
2000-09-08
Project End
2001-07-31
Budget Start
Budget End
Support Year
14
Fiscal Year
2000
Total Cost
Indirect Cost
Name
Cold Spring Harbor Laboratory
Department
Type
DUNS #
065968786
City
Cold Spring Harbor
State
NY
Country
United States
Zip Code
11724
Alexander, Joan; Kendall, Jude; McIndoo, Jean et al. (2018) Utility of Single-Cell Genomics in Diagnostic Evaluation of Prostate Cancer. Cancer Res 78:348-358
Huang, Yu-Han; Klingbeil, Olaf; He, Xue-Yan et al. (2018) POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer. Genes Dev 32:915-928
Tiriac, Hervé; Belleau, Pascal; Engle, Dannielle D et al. (2018) Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer. Cancer Discov 8:1112-1129
Naguib, Adam; Mathew, Grinu; Reczek, Colleen R et al. (2018) Mitochondrial Complex I Inhibitors Expose a Vulnerability for Selective Killing of Pten-Null Cells. Cell Rep 23:58-67
Forcier, Talitha L; Ayaz, Andalus; Gill, Manraj S et al. (2018) Measuring cis-regulatory energetics in living cells using allelic manifolds. Elife 7:
Bhagwat, Anand S; Lu, Bin; Vakoc, Christopher R (2018) Enhancer dysfunction in leukemia. Blood 131:1795-1804
Aberle, M R; Burkhart, R A; Tiriac, H et al. (2018) Patient-derived organoid models help define personalized management of gastrointestinal cancer. Br J Surg 105:e48-e60
Chen, Wei-Chia; Tareen, Ammar; Kinney, Justin B (2018) Density Estimation on Small Data Sets. Phys Rev Lett 121:160605
Khan, Jalal A; Maki, Robert G; Ravi, Vinod (2018) Pathologic Angiogenesis of Malignant Vascular Sarcomas: Implications for Treatment. J Clin Oncol 36:194-201
Albrengues, Jean; Shields, Mario A; Ng, David et al. (2018) Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice. Science 361:

Showing the most recent 10 out of 380 publications