Core - Biostatistics Facility

Taylor, Jeremy M.G.

Abstract

The Biostatistics Core continues to grow and enhance the service it provides to University of Michigan Comprehensive Cancer Center researchers. During 199 Biostatistics Core personnel collaborated with, consulted with, or interacted with 99 different UMCCC investigations from all Cancer Center programs on cancer research projects. Since the time of the last renewal Biostatistics Core personnel have co-authored 52 publications with UMCCC scientists with a further 16 submitted articles. The Biostatistics Core personnel collaborate with Cancer Center investigators on the development, design, analysis, interpretation and publication of cancer research projects. The Biostatistics Core is designed to provide both high level intellectual scientific input and serve level support to cancer research projects. The specific objectives of the core are to: collaborate with scientists in the formulation of research questions collaborate with clinical investigators on design of clinical research protocols. collaborate on the design and development of new research initiatives and new grant proposals. collaborate on statistical analysis of data from cancer research projects support the review and monitoring of clinical research protocols undertake methodological research leading to improved methods of design and analysis of specific cancer research data consult with investigators on appropriate statistical methods ane data analysis tools and review abstracts and manuscripts for statistical issues.

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Center Core Grants (P30)
• Project #: 5P30CA046592-15
• Application #: 6597016
• Project Start: 2002-06-01
• Project End: 2003-05-31
• Support Year: 15
• Fiscal Year: 2002

Institution

• Name: University of Michigan Ann Arbor
• DUNS #: 791277940
• City: Ann Arbor
• State: MI
• Country: United States
• Zip Code: 48109

Publications

Hoban, Connor W; Beesley, Lauren J; Bellile, Emily L et al. (2018) Individualized outcome prognostication for patients with laryngeal cancer. Cancer 124:706-716

Maust, Joel D; Frankowski-McGregor, Christy L; Bankhead 3rd, Armand et al. (2018) Cyclooxygenase-2 Influences Response to Cotargeting of MEK and CDK4/6 in a Subpopulation of Pancreatic Cancers. Mol Cancer Ther 17:2495-2506

Arthur, Anna E; Goss, Amy M; Demark-Wahnefried, Wendy et al. (2018) Higher carbohydrate intake is associated with increased risk of all-cause and disease-specific mortality in head and neck cancer patients: results from a prospective cohort study. Int J Cancer 143:1105-1113

Valenciaga, Anisley; Saji, Motoyasu; Yu, Lianbo et al. (2018) Transcriptional targeting of oncogene addiction in medullary thyroid cancer. JCI Insight 3:

Akkina, Sarah R; Kim, Roderick Y; Stucken, Chaz L et al. (2018) Is There a Difference in Staging and Treatment of Head and Neck Squamous Cell Tumors Between Tertiary Care and Community-Based Institutions? Laryngoscope Investig Otolaryngol 3:290-295

Anwar, Talha; Arellano-Garcia, Caroline; Ropa, James et al. (2018) p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasis. Nat Commun 9:2801

Giraldez, Maria D; Spengler, Ryan M; Etheridge, Alton et al. (2018) Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling. Nat Biotechnol 36:746-757

Hartlerode, Andrea J; Regal, Joshua A; Ferguson, David O (2018) Reversible mislocalization of a disease-associated MRE11 splice variant product. Sci Rep 8:10121

Fritsche, Lars G; Gruber, Stephen B; Wu, Zhenke et al. (2018) Association of Polygenic Risk Scores for Multiple Cancers in a Phenome-wide Study: Results from The Michigan Genomics Initiative. Am J Hum Genet 102:1048-1061

Haley, Henry R; Shen, Nathan; Qyli, Tonela et al. (2018) Enhanced Bone Metastases in Skeletally Immature Mice. Tomography 4:84-93