Biostatistics Core The Biostatistics Core personnel collaborate with Cancer Center investigators in the Basic Sciences, Clinical and Prevention/Control divisions on the development, design, analysis, interpretation and publication of cancer research projects. The Biostatistics Core is designed to provide both high level intellectual scientific input and service level support to cancer research projects. The specific objectives of the core are to: (i) collaborate with scientists in the formulation of research questions (ii) collaborate with clinical investigators on design of clinical research protocols (iii) collaborate on the design and development of new research initiatives and new grant proposals (iv) collaborate on statistical analysis and publication of data from cancer research projects (v) support the review, monitoring and oversight of clinical and prevention research protocols (vi) undertake methodological research leading to improved methods of design and analysis of specific cancer research data (vii) consult with investigators on appropriate statistical methods and data analysis tools and review abstracts and manuscripts for statistical issues (viii) Consult with investigators and data managers on efficient and accurate collection of protocol data (ix) Instruct scientists and clinical investigators in basic statistical methods The Biostatistics Core continues to grow and enhance the service it provides to all University of Michigan Comprehensive Cancer Center researchers. During each of the last 5 years Biostatistics Core personnel collaborated with, consulted with, or interacted with over 100 different UMCCC investigations from all programs on cancer research projects. Since the time of the last competing renewal Biostatistics Core personnel have co-authored 186 publications with UMCCC scientists.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA046592-22
Application #
7917281
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2009-06-01
Budget End
2010-05-31
Support Year
22
Fiscal Year
2009
Total Cost
$561,805
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Harvey, Innocence; Stephenson, Erin J; Redd, JeAnna R et al. (2018) Glucocorticoid-Induced Metabolic Disturbances Are Exacerbated in Obese Male Mice. Endocrinology 159:2275-2287
Schuetze, Scott M; Bolejack, Vanessa; Thomas, Dafydd G et al. (2018) Association of Dasatinib With Progression-Free Survival Among Patients With Advanced Gastrointestinal Stromal Tumors Resistant to Imatinib. JAMA Oncol 4:814-820
Wagner, Vivian P; Martins, Manoela D; Martins, Marco A T et al. (2018) Targeting histone deacetylase and NF?B signaling as a novel therapy for Mucoepidermoid Carcinomas. Sci Rep 8:2065
Hosoya, Tomonori; D'Oliveira Albanus, Ricardo; Hensley, John et al. (2018) Global dynamics of stage-specific transcription factor binding during thymocyte development. Sci Rep 8:5605
Schofield, Heather K; Tandon, Manuj; Park, Min-Jung et al. (2018) Pancreatic HIF2? Stabilization Leads to Chronic Pancreatitis and Predisposes to Mucinous Cystic Neoplasm. Cell Mol Gastroenterol Hepatol 5:169-185.e2
Su, Wenmei; Feng, Shumei; Chen, Xiuyuan et al. (2018) Silencing of Long Noncoding RNA MIR22HG Triggers Cell Survival/Death Signaling via Oncogenes YBX1, MET, and p21 in Lung Cancer. Cancer Res 78:3207-3219
Moody, Rebecca Reed; Lo, Miao-Chia; Meagher, Jennifer L et al. (2018) Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes. J Biol Chem 293:2125-2136
Ma, Vincent T; Boonstra, Philip S; Menghrajani, Kamal et al. (2018) Treatment With JAK Inhibitors in Myelofibrosis Patients Nullifies the Prognostic Impact of Unfavorable Cytogenetics. Clin Lymphoma Myeloma Leuk 18:e201-e210
Collins, Dalis; Fry, Christopher; Moore, Bethany B et al. (2018) Phagocytosis by Fibrocytes as a Mechanism to Decrease Bacterial Burden and Increase Survival in Sepsis. Shock :
Wang, Xuexiang; Dande, Ranadheer R; Yu, Hao et al. (2018) TRPC5 Does Not Cause or Aggravate Glomerular Disease. J Am Soc Nephrol 29:409-415

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