Biostatistics Core The Biostatistics Core personnel collaborate with Cancer Center investigators in the Basic Sciences, Clinical and Prevention/Control divisions on the development, design, analysis, interpretation and publication of cancer research projects. The Biostatistics Core is designed to provide both high level intellectual scientific input and service level support to cancer research projects. The specific objectives of the core are to: (i) collaborate with scientists in the formulation of research questions (ii) collaborate with clinical investigators on design of clinical research protocols (iii) collaborate on the design and development of new research initiatives and new grant proposals (iv) collaborate on statistical analysis and publication of data from cancer research projects (v) support the review, monitoring and oversight of clinical and prevention research protocols (vi) undertake methodological research leading to improved methods of design and analysis of specific cancer research data (vii) consult with investigators on appropriate statistical methods and data analysis tools and review abstracts and manuscripts for statistical issues (viii) Consult with investigators and data managers on efficient and accurate collection of protocol data (ix) Instruct scientists and clinical investigators in basic statistical methods The Biostatistics Core continues to grow and enhance the service it provides to all University of Michigan Comprehensive Cancer Center researchers. During each of the last 5 years Biostatistics Core personnel collaborated with, consulted with, or interacted with over 100 different UMCCC investigations from all programs on cancer research projects. Since the time of the last competing renewal Biostatistics Core personnel have co-authored 186 publications with UMCCC scientists.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA046592-23
Application #
8147794
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2010-06-01
Budget End
2011-05-31
Support Year
23
Fiscal Year
2010
Total Cost
$565,417
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Cho, Chun-Seok; Park, Hwan-Woo; Ho, Allison et al. (2018) Lipotoxicity induces hepatic protein inclusions through TANK binding kinase 1-mediated p62/sequestosome 1 phosphorylation. Hepatology 68:1331-1346
Chockley, Peter J; Chen, Jun; Chen, Guoan et al. (2018) Epithelial-mesenchymal transition leads to NK cell-mediated metastasis-specific immunosurveillance in lung cancer. J Clin Invest 128:1384-1396
Hertz, Daniel L; Kidwell, Kelley M; Vangipuram, Kiran et al. (2018) Paclitaxel Plasma Concentration after the First Infusion Predicts Treatment-Limiting Peripheral Neuropathy. Clin Cancer Res 24:3602-3610
Parsels, Leslie A; Karnak, David; Parsels, Joshua D et al. (2018) PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors. Mol Cancer Res 16:222-232
Menghrajani, Kamal; Boonstra, Philip S; Mercer, Jessica A et al. (2018) Predictive models for splenic response to JAK-inhibitor therapy in patients with myelofibrosis. Leuk Lymphoma :1-7
Xiong, Xiufang; Liu, Xia; Li, Haomin et al. (2018) Ribosomal protein S27-like regulates autophagy via the ?-TrCP-DEPTOR-mTORC1 axis. Cell Death Dis 9:1131
Yu, Lei; Jearawiriyapaisarn, Natee; Lee, Mary P et al. (2018) BAP1 regulation of the key adaptor protein NCoR1 is critical for ?-globin gene repression. Genes Dev 32:1537-1549
Nanba, Kazutaka; Omata, Kei; Else, Tobias et al. (2018) Targeted Molecular Characterization of Aldosterone-Producing Adenomas in White Americans. J Clin Endocrinol Metab 103:3869-3876
Maust, Joel D; Frankowski-McGregor, Christy L; Bankhead 3rd, Armand et al. (2018) Cyclooxygenase-2 Influences Response to Cotargeting of MEK and CDK4/6 in a Subpopulation of Pancreatic Cancers. Mol Cancer Ther 17:2495-2506
Hoban, Connor W; Beesley, Lauren J; Bellile, Emily L et al. (2018) Individualized outcome prognostication for patients with laryngeal cancer. Cancer 124:706-716

Showing the most recent 10 out of 1493 publications