Abstract

(PRECLINICAL IMAGING & COMPUTATIONAL ANALYSIS) The Preclinical Imaging and Computational Analysis (PICA) Shared Resource (SR), previously called Tumor Imaging, was established in 1986 and has been continuously funded by the CCSG since 1988. Early in this project period, the University of Michigan Comprehensive Cancer Center (UMCCC) decided to separate the preclinical and clinical components of the SR in order to optimize growth and development. The preclinical component is now the PICA SR whereas the clinical imaging component is supported by non-CCSG funds via the UMCCC Clinical Trials Support Unit. These changes were endorsed by Senior Leadership and the External Advisory Board. The SR gives UMCCC members preferred access to exceptional imaging expertise and highly specialized equipment and supports proof of principle studies for eventual transition to human imaging studies.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA046592-29
Application #
9488236
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2018-06-01
Budget End
2019-05-31
Support Year
29
Fiscal Year
2018
Total Cost
Indirect Cost

  Institution

Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109

  Publications

Jiagge, Evelyn; Jibril, Aisha Souleiman; Davis, Melissa et al. (2018) Androgen Receptor and ALDH1 Expression Among Internationally Diverse Patient Populations. J Glob Oncol :1-8
Bowers, Emily; Slaughter, Anastasiya; Frenette, Paul S et al. (2018) Granulocyte-derived TNF? promotes vascular and hematopoietic regeneration in the bone marrow. Nat Med 24:95-102
Holt, Melissa C; Assar, Zahra; Beheshti Zavareh, Reza et al. (2018) Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors. Biochemistry 57:6604-6614
Wang, Yin; Day, Mark L; Simeone, Diane M et al. (2018) 3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer. J Vis Exp :
Suresh, Krithika; Owen, Dawn; Bazzi, Latifa et al. (2018) Using Indocyanine Green Extraction to Predict Liver Function After Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma. Int J Radiat Oncol Biol Phys 100:131-137
O'Dwyer, David N; Zhou, Xiaofeng; Wilke, Carol A et al. (2018) Lung Dysbiosis, Inflammation, and Injury in Hematopoietic Cell Transplantation. Am J Respir Crit Care Med 198:1312-1321
El Kadi, Najwa; Wang, Luo; Davis, April et al. (2018) The EGFR T790M Mutation Is Acquired through AICDA-Mediated Deamination of 5-Methylcytosine following TKI Treatment in Lung Cancer. Cancer Res 78:6728-6735
Feng, Mary; Suresh, Krithika; Schipper, Matthew J et al. (2018) Individualized Adaptive Stereotactic Body Radiotherapy for Liver Tumors in Patients at High Risk for Liver Damage: A Phase 2 Clinical Trial. JAMA Oncol 4:40-47
Xiong, Yi; Torsoni, Adriana Souza; Wu, Feihua et al. (2018) Hepatic NF-kB-inducing kinase (NIK) suppresses mouse liver regeneration in acute and chronic liver diseases. Elife 7:
Eisenberg, Marisa C; Campredon, Lora P; Brouwer, Andrew F et al. (2018) Dynamics and Determinants of HPV Infection: The Michigan HPV and Oropharyngeal Cancer (M-HOC) Study. BMJ Open 8:e021618

Showing the most recent 10 out of 1493 publications