) The goal of the Clinical and Community Cancer Prevention and Control Program (CCCPCP) is to foster inter-disciplinary and inter-institutional research in cancer primary prevention, early detection, and treatment outcome studies in order to reduce the future incidence and death rates from cancer in Colorado, the Rocky Mountain Region, and the Nation. Research projects include phase III clinical trials of chemoprevention, screening, and behavioral interventions, and community-based studies of cancer prevention and cancer outcomes. The CCCPC Program is under the direction of Dr. Al Marcus (Acting CCCPC Program Leader), who is assisted by Mr. Kyle Osborn (DCPC Administrator). The CCCPCP includes 56 investigators (30 full members and 26 associate members) representing ten departments and centers in the University of Colorado Schools of Medicine and Nursing and several UCCC collaborating institutions, including the AMC Cancer Research Center. In 1999, CCCPC members have 61 grants and $7.7 million in direct costs in extramural support, including 28 grants and $5.5 million in direct costs from the National Cancer Institute. Over the past five years there has been an increase in the collaborations between UCCC members at the UCHSC and at the AMC, the Colorado Department of Public Health and Environment, the Colorado Foundation for Medical Care, and the other cancer centers in this region (New Mexico, Arizona, Utah). We expect even greater inter-institutional collaboration in the future as we continue to further develop a broad-based research program with an emphasis on the translation of behavioral and clinical research findings for the benefit of people in Colorado, the Rocky Mountain Region, and the Nation. This work will be supported by the new Survey Research Core and the developing cores in Health Communications and Recruitment/Retention. Recruitment are planned for a new CCCPC Program Leader, and for investigators in psychosocial oncology, community cancer research, and outcomes research.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA046934-14
Application #
6488516
Study Section
Subcommittee E - Prevention &Control (NCI)
Project Start
1988-03-01
Project End
2006-01-31
Budget Start
Budget End
Support Year
14
Fiscal Year
2001
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Type
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
Dodson, R Blair; Powers, Kyle N; Gien, Jason et al. (2018) Intrauterine growth restriction decreases NF-?B signaling in fetal pulmonary artery endothelial cells of fetal sheep. Am J Physiol Lung Cell Mol Physiol 315:L348-L359
Kumar, Rahul; Deep, Gagan; Wempe, Michael F et al. (2018) Procyanidin B2 3,3?-di-O-gallate induces oxidative stress-mediated cell death in prostate cancer cells via inhibiting MAP kinase phosphatase activity and activating ERK1/2 and AMPK. Mol Carcinog 57:57-69
Richmond, Craig S; Oldenburg, Darby; Dancik, Garrett et al. (2018) Glycogen debranching enzyme (AGL) is a novel regulator of non-small cell lung cancer growth. Oncotarget 9:16718-16730
Zhang, Lingdi; Zhou, Hengbo; Li, Xueni et al. (2018) Eya3 partners with PP2A to induce c-Myc stabilization and tumor progression. Nat Commun 9:1047
Riching, Andrew S; Zhao, Yuanbiao; Cao, Yingqiong et al. (2018) Suppression of Pro-fibrotic Signaling Potentiates Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts into Induced Cardiomyocytes. J Vis Exp :
Saldi, Tassa; Fong, Nova; Bentley, David L (2018) Transcription elongation rate affects nascent histone pre-mRNA folding and 3' end processing. Genes Dev 32:297-308
Wilson, Michael L; Ayers, Stephanie; Berney, Daniel et al. (2018) Improving Anatomic Pathology in Sub-Saharan Africa to Support Cancer Care. Am J Clin Pathol 149:310-315
Wysoczynski-Horita, Christina L; Boursier, Michelle E; Hill, Ryan et al. (2018) Mechanism of agonism and antagonism of the Pseudomonas aeruginosa quorum sensing regulator QscR with non-native ligands. Mol Microbiol 108:240-257
Collins, Keagan P; Jackson, Kristen M; Gustafson, Daniel L (2018) Hydroxychloroquine: A Physiologically-Based Pharmacokinetic Model in the Context of Cancer-Related Autophagy Modulation. J Pharmacol Exp Ther 365:447-459
Villalobos, Victor Manuel; Hall, Francis; Jimeno, Antonio et al. (2018) Long-Term Follow-Up of Desmoid Fibromatosis Treated with PF-03084014, an Oral Gamma Secretase Inhibitor. Ann Surg Oncol 25:768-775

Showing the most recent 10 out of 1634 publications