Abstract

) The Prostate and Urologic Cancer Program (PUCP) of the UPCI focuses on the basic and clinical study of prostate and other genitourinary (GU) cancers. The Program's goals are (1) to develop improved understanding of the biology of prostate and other GU cancers; (2) to develop new diagnostic and therapeutic approaches to these tumors; and (3) to develop new concepts applicable to the prevention of prostate or other GU cancers. These goals are approached through basic science investigations, translational research studies, and clinical trials. The leadership of the Program consists of Dr. Robert H. Getzenberg, Assistant Professor of Pathology, Surgery, Medicine and Pharmacology and Director of Research, PUCP and Dr. Donald L. Trump, Professor of Medicine and Surgery, Chief of the Division of Hematology/Oncology and UPCI Deputy Director for Clinical Investigations. The PUCP is a very interactive program including members of Urology, Hematology/Oncology, Endocrinology, Pathology and other basic science and clinical departments, all actively participating in the Program. Many of the grants and papers resulting from the Program are cooperative efforts among PUCP members.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA047904-12
Application #
6212115
Study Section
Subcommittee G - Education (NCI)
Project Start
1988-08-01
Project End
2004-07-30
Budget Start
Budget End
Support Year
12
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
University of Pittsburgh
Department
Type
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213

  Publications

Ander, Stephanie E; Rudzki, Elizabeth N; Arora, Nitin et al. (2018) Human Placental Syncytiotrophoblasts Restrict Toxoplasma gondii Attachment and Replication and Respond to Infection by Producing Immunomodulatory Chemokines. MBio 9:
Hartmaier, R J; Trabucco, S E; Priedigkeit, N et al. (2018) Recurrent hyperactive ESR1 fusion proteins in endocrine therapy-resistant breast cancer. Ann Oncol 29:872-880
Palliyaguru, Dushani L; Yuan, Jian-Min; Kensler, Thomas W et al. (2018) Isothiocyanates: Translating the Power of Plants to People. Mol Nutr Food Res 62:e1700965
Yoon, Joo Heung; Nouraie, Mehdi; Chen, Xiaoping et al. (2018) Characteristics of lung cancer among patients with idiopathic pulmonary fibrosis and interstitial lung disease - analysis of institutional and population data. Respir Res 19:195
Nikiforova, Marina N; Mercurio, Stephanie; Wald, Abigail I et al. (2018) Analytical performance of the ThyroSeq v3 genomic classifier for cancer diagnosis in thyroid nodules. Cancer 124:1682-1690
Steel, Jennifer L; Terhorst, Lauren; Collins, Kevin P et al. (2018) Prospective Analyses of Cytokine Mediation of Sleep and Survival in the Context of Advanced Cancer. Psychosom Med 80:483-491
Luthra, Soumya; Chandran, Uma; Diergaarde, Brenda et al. (2018) Expression of reactive species related genes is associated with patient survival in luminal B breast cancer. Free Radic Biol Med 120:170-180
Saydmohammed, Manush; Tsang, Michael (2018) High-Throughput Automated Chemical Screens in Zebrafish. Methods Mol Biol 1683:383-393
Steinman, Justin; Epperly, Michael; Hou, Wen et al. (2018) Improved Total-Body Irradiation Survival by Delivery of Two Radiation Mitigators that Target Distinct Cell Death Pathways. Radiat Res 189:68-83
Yockey, Laura J; Jurado, Kellie A; Arora, Nitin et al. (2018) Type I interferons instigate fetal demise after Zika virus infection. Sci Immunol 3:

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