The Animal Facility is actually an animal care program, consisting of staff, services and facilities dedicated to meeting the animal-dependent needs of the research programs of the University of Pittsburgh Cancer Institute. The goal of the Facility is to provide expertise, advice, facilities, and personnel as well as training and assistance, whenever cancer-related investigations require the use of animal models. A new facility, of approximately 12, 000 net sq. ft., in the Hillman Cancer Center, was validated and opened in October of 2002, to add to the approximately 850 net sq. ft. facility located within the Shadyside Urolical Surgical Resource(SUSR) facility on the ground floor of UPMC Shadyside Hospital. These facilities are designed, managed and dedicated to maintaining specific pathogen-free (SPF) rodent populations, using barrier and microisolator caging techniques. This core is an integral component of the University's overall Animal Care Program, that is overseen by the Institutional Animal Care and Use Committee. This program is registered with the USDA (23-R0016) and maintains a letter of assurance with the Public Health Service of the NIH (A3187-01). It is fully accredited by the Association for the Assessment and Accreditation for Laboratory Animal Care International (AAALAC Int.). Notice of last full accreditation status was received in March of 2003.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA047904-17
Application #
6989508
Study Section
Subcommittee G - Education (NCI)
Project Start
2004-09-22
Project End
2009-07-31
Budget Start
2004-09-22
Budget End
2005-07-31
Support Year
17
Fiscal Year
2004
Total Cost
$69,913
Indirect Cost
Name
University of Pittsburgh
Department
Type
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Correa, Andres F; Toussi, Amir; Amin, Milon et al. (2018) Small Renal Masses in Close Proximity to the Collecting System and Renal Sinus Are Enriched for Malignancy and High Fuhrman Grade and Should Be Considered for Early Intervention. Clin Genitourin Cancer 16:e729-e733
Wang, Yi-Jun; Fletcher, Rochelle; Yu, Jian et al. (2018) Immunogenic effects of chemotherapy-induced tumor cell death. Genes Dis 5:194-203
Bakkenist, Christopher J; Lee, James J; Schmitz, John C (2018) ATM Is Required for the Repair of Oxaliplatin-Induced DNA Damage in Colorectal Cancer. Clin Colorectal Cancer 17:255-257
Low, Carissa A; Bovbjerg, Dana H; Ahrendt, Steven et al. (2018) Fitbit step counts during inpatient recovery from cancer surgery as a predictor of readmission. Ann Behav Med 52:88-92
Tasdemir, Nilgun; Bossart, Emily A; Li, Zheqi et al. (2018) Comprehensive Phenotypic Characterization of Human Invasive Lobular Carcinoma Cell Lines in 2D and 3D Cultures. Cancer Res 78:6209-6222
Mazharuddin, Samir; Chattopadhyay, Anuja; Levy, Moshe Y et al. (2018) IRF2BP2-RARA t(1;17)(q42.3;q21.2) APL blasts differentiate in response to all-trans retinoic acid. Leuk Lymphoma 59:2246-2249
Basudan, Ahmed; Priedigkeit, Nolan; Hartmaier, Ryan J et al. (2018) Frequent ESR1 and CDK Pathway Copy-Number Alterations in Metastatic Breast Cancer. Mol Cancer Res :
Beumer, Jan H; Chu, Edward; Allegra, Carmen et al. (2018) Therapeutic Drug Monitoring in Oncology: International Association of Therapeutic Drug Monitoring and Clinical Toxicology Recommendations for 5-Fluorouracil Therapy. Clin Pharmacol Ther :
Leng, Shuguang; Diergaarde, Brenda; Picchi, Maria A et al. (2018) Gene Promoter Hypermethylation Detected in Sputum Predicts FEV1 Decline and All-Cause Mortality in Smokers. Am J Respir Crit Care Med 198:187-196
Zhang, Jiliang; Zhang, Shaojuan; Liu, Yang et al. (2018) Combined CB2 receptor agonist and photodynamic therapy synergistically inhibit tumor growth in triple negative breast cancer. Photodiagnosis Photodyn Ther 24:185-191

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