The overall strategic objective of the Drew/Meharry/Morehouse Consortium Cancer Center is to conduct research aimed at reducing the high incidence and mortality from cancer in the black population. The three private medical schools represent a unique national resource with a strong commitment to this goal. The general approach has been to focus on cancer prevention and control, including an initial effort to enhance the enrolment of minorities into state-of-the-art treatment. This will continue to be the overall strategy of the Center along with encouraging the joint participation of those who are interested in the basic sciences and those with an interest in exploring ethnic differences in disease. The Center is also the focal point for mobilizing black leaderss nationally through the supplemental grant on the National Blasck Leadership Initiative in Cancer. Special attention has been given to lung, breast, cervical and prostate cancer and the highest priorities currently include smoking, early detection and clinical trials but there is increasing interest in studying interventions related to diet and to occupation. The institutions have formed strong linkages with each other and with their respective health departments and the Center has been strengthened by its association with centers in majority institutions. This proposal seeks core support for five years for senior leadership, program directors, administration, four shared resources (Epi-stat, editorial, survey research and clinical trials), planning and evaluation and development funds for the development of nutrition and occupational research.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA049095-06
Application #
3101871
Study Section
Special Emphasis Panel (SRC (S1))
Project Start
1988-09-30
Project End
1995-05-31
Budget Start
1993-09-30
Budget End
1994-05-31
Support Year
6
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Charles R. Drew University of Medicine & Science
Department
Type
Schools of Medicine
DUNS #
785877408
City
Los Angeles
State
CA
Country
United States
Zip Code
90059
Schlundt, David G; Hargreaves, Margaret K; Buchowski, Maciej S (2003) The Eating Behavior Patterns Questionnaire predicts dietary fat intake in African American women. J Am Diet Assoc 103:338-45
Hargreaves, M K; Schlundt, D G; Takizala, Z et al. (2003) A taxonomy of obstacles to breast examinations in African American women. Cell Mol Biol (Noisy-le-grand) 49:1219-28
Bhat, Hari K; Vadgama, Jaydutt V (2002) Role of estrogen receptor in the regulation of estrogen induced amino acid transport of System A in breast cancer and other receptor positive tumor cells. Int J Mol Med 9:271-9
Wu, Yanyuan; Saldana, Laura; Chillar, Ram et al. (2002) Plasma vascular endothelial growth factor is useful in assessing progression of breast cancer post surgery and during adjuvant treatment. Int J Oncol 20:509-16
Hargreaves, Margaret K; Schlundt, David G; Buchowski, Maciej S (2002) Contextual factors influencing the eating behaviours of African American women: a focus group investigation. Ethn Health 7:133-47
Shen, D; Wu, Y; Subbarao, M et al. (2000) Mutation analysis of BRCA1 gene in African-American patients with breast cancer. J Natl Med Assoc 92:29-35
Bhat, H K; Vadgama, J V (2000) Hamster estrogen receptor cDNA: cloning and mRNA expression. J Steroid Biochem Mol Biol 72:47-53
Vadgama, J V; Wu, Y; Shen, D et al. (2000) Effect of selenium in combination with Adriamycin or Taxol on several different cancer cells. Anticancer Res 20:1391-414
Liu, W; Vadgama, J V (2000) Identification and characterization of amino acid starvation-induced CD24 gene in MCF-7 human breast cancer cells. Int J Oncol 16:1049-54
Shen, D; Wu, Y; Chillar, R et al. (2000) Missense alterations of BRCA1 gene detected in diverse cancer patients. Anticancer Res 20:1129-32

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